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Now showing items 18031-18050 of 41699
Exploring the molecular bases underlying complex diseases and drug action through a systems biology approach
Las enfermedades y otros procesos biológicos son complejos y están producidos por la interacción de múltiples factores genéticos y ambientales. En las últimas décadas, los métodos tradicionales reduccionistas han dado paso ...
Exploring the molecular basis of dairy production and viability traits in Murciano-Granadina goats with genomic, metagenomic and transcriptomic approaches
En aquesta tesi, hem volgut investigar les bases genètiques dels caràcters lleters i morfològics de les cabres Murciano-Granadina, així com explorar la composició microbiana de diversos tipus de formatges caprins. ...
Exploring the Multifaceted Powers of Solanum lycopersicum Heme-Binding Protein 2 (SlHBP2): A Dynamic Investigation into Antimicrobial, plant Immune-Boosting, and Anticancer Potential
This research investigated the mechanisms of action of Solanum lycopersicum heme-binding protein (SlHBP2) against the bacterial pathogen Pseudomonas syringae pv. tomato DC3000 (Pst) and SlHBP2 potential for boosting plant ...
Exploring the pharmacological properties of human antimicrobial ribonucleases
Aquesta tesi s’enfoca en la caracterització estructural i funcional de les propietats biològiques de les RNases antimicrobianes de la superfamília de la RNasa A. Concretament, s’han assolit els següents objectius a curt ...
Exploring the potential for the selective breeding of Nesidiocoris Tenuis: A study of its genetics and feeding behavior
Nesidiocoris tenuis is a zoophytopbagous insect used in tomato crops to control key pests. Its ability to foed on plant tissues gives it the advantages to be able to establish in the crops before the arrival afthe pest, ...
Exploring the potential usage of underused urban space: Hajj sites in Mecca as case study
The term Underused Urban Spaces (UUS) refers to spaces within urban areas that have become unused, or that are being used to a lesser degree than they could or should be. The emergence of such spaces has therefore encouraged ...
Exploring the Power of Self-efficacy at Work: Some Empirical Studies from the Social Cognitive Theory
Con el desarrollo de esta tesis se pretendía profundizar en el estudio de las creencias de eficacia, utilizando la Teoría Social Cognitiva (TSC) de Albert Bandura como marco teórico. Esta teoría asume que las personas, en ...
Exploring the regulation and function of TIGAR in cancer cells
The TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) gene was described in 2006 by Dr. Karen Vousden's group in response to the induction of the tumour suppressor gene p53. Since then, numerous studies have focused ...
Exploring the regulatory mechanisms of the S. cerevisiae Ppz1 protein phosphatase and the molecular basis for its toxicity
Uno de los más notables componentes en la homeostasis de cationes en levaduras es la proteína fosfatasa Ppz1. El papel de Ppz1 es doble: inhibe la entrada de potasio mediante el control de la actividad de los transportadores ...
Exploring the role of climate variability and change in the spillover of zoonotic diseases: towards the development of Early Warning Systems (RWS)
The primary goal of this PhD is to deepen our understanding and improve the modeling capacity of zoonotic spillover, the multilevel process by which pathogens manage to overcome a series of natural barriers and infect other ...
Exploring the role of differential expression of splicing factors and regulators in tissue-specific alternative splicing
Alternative splicing (AS) is an important step in the pathway of gene expression and regulation. The splicing process is catalyzed by the Spliceosome, a complex molecular machinery that is dynamically assembled on the ...
Exploring the role of DYRK1A in RNA polymerase III transcription : DYRK1A as a potential regulator of TFIIIC
The kinase DYRK1A (dual-specificity tyrosine-regulated kinase 1A) is a dosage-sensitive gene, since both haploinsufficiency and overexpression when in trisomy lead to pathological phenotypes in humans. In this Thesis, the ...
Exploring the role of genetics and environment on the neural substrates of word and rule learning
L’origen ambiental i genètic de les diferències individuals en l’aprenentatge de paraules i regles gramaticals és desconegut. Per aquest motiu es van realitzar dos estudis. En el primer, dos grups de bessons, monozigòtics ...
Exploring the role of glycans: A new frontier in disease biomarker research
Els glicans juguen un paper crucial en diversos processos biològics i han emergit com a potencials biomarcadors en la recerca biomèdica i les aplicacions clíniques. Aquests carbohidrats estan implicats en la comunicació ...
Exploring the role of NR2E3 in photoreceptor cell fate determination
The transcription factor NR2E3 participates in photoreceptor cell fate determination as it functions as both transcriptional repressor of cone genes and activator of rod genes. Mutations in NR2E3 cause retinitis pigmentosa ...
Exploring the Role of Third Party Logistic (TPL) Companies as Enablers for Collaborative Systems and Blue Ocean Strategy in Supply Chain Management
[eng] This doctoral thesis investigates the potential of third-party logistics (TPL) companies as key facilitators of collaborative systems and the implementation of the blue ocean strategy within the realm of supply chain ...
Exploring the topical structure of short text through probability models : from tasks to fundamentals
Recent technological advances have radically changed the way we communicate. Today’s communication has become ubiquitous and it has fostered the need for information that is easier to create, spread and consume. As a ...
Exploring the Universe with Quasar Absorption Spectra: correlations among tracers of the mass density field and the impact of ionizing background intensity fluctuations
The work we present in this manuscript revolves around the use of quasar spectra to probe the Universe. Absorption features in the electromagnetic spectrum of bright distant quasars by ionized hydrogen give us access to ...
Exploring the water-energy nexus in urban and tourist areas of the western mediterranean. Empirical findings from Benidorm and Barcelona
La tesi analitza el Nexe Aigua-Energia (WEN) a través d'una metodologia mixta centrant-se en el metabolisme urbà de l'aigua a Benidorm i Barcelona. El cas de Benidorm examina el subministrament d'aigua a escala municipal ...
Exploring the Zn deficiency hypothesis to explain the beneficial effect of therapeutic ZnO in weaning pigs
L’objectiu general de la present tesi doctoral és estudiar l’estatus de Zn dels garrins deslletats i com aquest es veu afectat pel deslletament i la suplementació dietària de Zn, com són els nivells farmacològics de ZnO ...
