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Now showing items 21672-21691 of 43196
Identification de facteurs d'intégration quantitatifs et qualitatifs des néologismes à la langue spécialisée médicale: une analyse sur corpus diachronique entre 2007 et 2015
La evolución del lenguaje médico refleja los avances médicos y se caracteriza por la creación neológica destinada a nombrar nuevos descubrimientos e innovaciones. Por lo tanto, la creación neológica, la variación terminológica ...
Identification of a new deadenylation negative feedback loop that regulates meiotic progression
Els oòcits de vertebrats es troben aturats a la profase I de la primera meiosi (PI). Durant el procés anomenat oogènesi, els oòctits sintetitzen i emmagatzemen grans quantitats d'ARN missatgers(ARNm)que els seran necessaris ...
Identification of a risk transcriptome and proteome in Parkinson’s disease, Dementia with Lewy bodies and rapidly progressive Dementia with Lewy bodies
Parkinson's disease (PD) is a neurodegenerative disorder characterized by movement impairment, or parkinsonism, for which there is still no cure. The manifest clinical signs result from neuronal loss of more ...
Identification of altered regulatory interactions in disease
Gene regulation is a complex biological process that requires the coordinated interaction of different molecules. The integrity of the underlying mechanisms ensures the correct expression of genes that maintain cell ...
Identification of black carbon contributions in oceanic sediments using benzene polycarboxylic acid markers
El carboni negre (BC) abasta una àmplia gamma de materials orgànics derivats de la combustió que són químicament i estructuralment heterogenis. Constitueix una fracció significativa de la matèria orgànica acumulada als ...
Identification of clinically relevant genetic variation in immune-mediated inflammatory diseases using genome-wide approaches
Rheumatoid arthritis, psoriasis, psoriatic arthritis, systemic lupus erythematosus, Crohn’s disease and ulcerative colitis are six of the most prevalent immune-mediated inflammatory diseases (IMIDs) and are associated with ...
Identification of deubiquitinating enzyme genes relevant for the regulation of retina-specific genes
Protein post-translational modifications are regulatory mechanisms that cells use in response to intra- and extracellular signals. These signals modulate a panoply of conjugating enzymes that modify proteins post-translationally ...
Identification of differential biological mechanisms between pregnancy and postpartum in Rheumatoid Arthritis
L’embaràs a l’Artritis Reumatoide (AR) proporciona un model únic per l’estudi dels mecanismes biològics de la malaltia. Durant l’embaràs, generalment, es produeix una interrupció transitòria de l’activitat de l’AR que es ...
Identification of environmental variables in Drosophila melanogaster natural populations
Entender cómo las especies se adaptan al ambiente es aún una pregunta sin resolver en el campo de la Biología Evolutiva. Mientras el foco principal siempre ha estado en la base genética, los factores ambientales responsables ...
Identification of genetic determinants of breast cancer metastasis to the bone
El objetivo de esta tesis era identificar determinantes genéticos de cáncer de mama con metástasis óseas. Para ello se utilizó un enfoque integral que se sustenta en células humanas de cáncer de mama, modelos experimentales ...
Identification of genetic modifiers of penetrance in human inherited disease
Understanding the molecular basis of human inherited disease is a challenging task due to the complexity of mapping the genotype to the phenotype. The study of diseases running in families has shown that the inheritance ...
Identification of Genetic Susceptibility Factors for Fibromyalgia / Identificació de factors de susceptibilitat genètica per a fibromiàlgia
Fibromyalgia (FM) is a highly disabling syndrome defined by a low pain threshold and a permanent state of pain. Widespread pain is accompanied by a constellation of symptoms such as fatigue, sleep disturbances and cognitive ...
Identification of HIV-1 reactivating quinoline compounds as bromodomain inhibitors
Tras la infección por VIH-1, el establecimiento de un depósito de células T en reposo infectadas latentemente con VIH impide la erradicación del virus en pacientes. Para lograr la erradicación, la terapia retroviral existente ...
Identification of immune biomarkers for use in early HIV detection and monitoring in sub-Saharan Africa = Identificación de biomarcadores de respuesta inmunitaria para la detección temprana y monitorización del VIH en África sub-Sahariana
BACKGROUND AND RATIONALE Acute HIV infection (AHI) is the period between the acquisition of the human immunodeficiency virus (HIV) and the development of HIV-specific antibodies that define seroconversion. AHI is ...
Identification of immunovirological factors that determine an extremely low viral reservoir: approaching the cure of HIV-1 infection
Gairebé 40 milions de persones viuen actualment amb el virus de la immunodeficiència humana tipus 1 (VIH-1) al món, i més de 30 milions de morts s’atribueixen al VIH-1 des del començament de l’epidèmia. El desenvolupament ...
Identification of material properties and phase distribution of heterogeneous materials through data-driven computational methods : towards an enhanced constitutive space
Identifying the constitutive relations of materials is an essential task to understand their behavior. Classical methods like testing can be effective in understanding these relationships, but introducing models can lead ...
Identification of mechanisms of acquired resistance to taxanes in triple negative breast cancer using patient-derived xenografts: a step closer to clinics
Chemotherapy is a general treatment for most breast tumors and depending on breast cancer subtype combination with targeted anti-hormonal or anti-HER2 therapy is conducted. Taxane-based regimens constitute the most common ...
Identification of Metabolites as Biomarkers and Mediators of Inflammation in Inflammatory Arthritis
L’artritis inflamatòria representa una gran càrrega social i econòmica tot i els recents avenços terapèutics. Malgrat un millor coneixement dels mecanismes patogénics, l’elecció de l’tractament encara es realitza a manera ...
Identification of microcrystalline phases in Lead Glazes of ceramics from 17th-19th centuries: archaeometric implications
Crystalline phases inside ancient glazes can have different origins: unreacted compounds (thus already formed before the glaze formation), crystallites developed during the glaze production or devitrification crystals ...
Identification of MIDORI: a novel microprotein that regulates epithelial-mesenchymal plasticity
Avançament recents en les tècniques de perfilat de ribosomes, peptidòmica i anàlisi bioinformàtic han revelat que moltes regions genòmiques que van ser anotades com no codificants, en realitat codifiquen petites proteïnes ...
