Cebadas dísticas españolas (Hordeum vulgare L.): filogenia,bioquímica y aplicación potencial en programas de mejora 

Moralejo Vidal, Mª Angeles (Date of defense: 1993-05-20)

Ceci est mon testament: Marc-Antoine Laugier 

Restrepo Hernández, Fabio (Date of defense: 2011-07-12)

The demolition the monolithic interpretation the engraving, which accompanies as Irontispiece Marc-Antoine Laugier's Essai sur l'Architecture, object the present work, aims to liberate the question about the origin ...

Ceci n'est pas une épidémie: Sobre las pipas de fumar y la gripe como dispositivo de saber-poder. 

Cárdenas Olesti, Noèlia (Date of defense: 2016-02-02)

La investigación que se presenta a continuación pretende visibilizar y explicar cómo los saberes disponibles sobre la gripe, transmitidos a través de los medios de comunicación, forman parte del proceso de control y gobierno ...

Cell base assays to investigate the functional relevance of HLH genetic variants 

Viñas Giménez, Laura (Date of defense: 2019-11-29)

La linfohistiocitosis hemofagocítica (HLH) es un trastorno hiperinflamatorio potencialmente mortal causado por una respuesta inmunitaria incontrolada y disfuncional. Las mutaciones en los genes implicados conducen a la ...

Cell culture interfaces for different organ-on-chip applications: from photolithography to rapid-prototyping techniques with sensor embedding 

Paoli, Roberto (Date of defense: 2019-12-09)

Despite the last 60 years have seen major advances in many scientific and technological inputs of drug Research and Development, the number of new molecules hitting the market per billion US dollars of R&D spending has ...

Cell cycle checkpoints in Caenorhabditis elegans: the 14-3-3 gene par-5 is required for germline development and DNA damage response / Checkpoints del ciclo celular en Caenorhabditis elegans: el gen 14-3-3, par-5, es necesario para el desarrollo y respuesta al daño genómico de la línea germinal 

Aristizábal Corrales, David (Date of defense: 2012-06-13)

14-3-3 proteins have been extensively studied from yeast to mammals, and are associated with multiple roles ranging from fundamental processes such as cell cycle, apoptosis and stress response to diseases such as ...

Cell death and cytokine-mediated inflammatory responses to glucose deprivation in cancer cells 

Püschel, Franziska (Date of defense: 2019-10-31)

Metabolic alterations in cancer cells are primarily caused by oncogenic mutations and cancer cells are more dependent on glucose compared to non-transformed tissue. Targeting the cancer metabolism opens up a new strategy ...

Cell derived-extracellular matrix scaffolds with polylactic acid microcarriers for tissue engineering and cell therapy 

Cano Torres, Irene (Date of defense: 2019-04-05)

Organ shortage for transplantation and the need for new therapies for the treatment of tissular damages have driven the development of an exciting field in research, called tissue engineering (TE). Its potential entails ...

Cell Stress and RNA Splicing in Amyotrophic Lateral Sclerosis: Novel Opportunities for Therapeutic Development 

Torres Cabestany, Pascual (Date of defense: 2021-02-26)

L'ELA és una malaltia neurodegenerativa multifactorial. Atès que actualment és una malaltia incurable sense una causa coneguda, els esforços per descobrir noves dianes terapèutiques estan ben justificats. L'evidència ...

Cell wall composition in relation to photosynthesis 

Roig Oliver, Margalida (Date of defense: 2022-04-05)

[eng] Photosynthesis is an essential process for plants. To comprehend how diffusive and biochemical CO2 processes involved in photosynthesis occur is of great relevance to understand plant physiology. For decades, ...

Cell-adhesive nanopatterns for musculoskeletal tissue engineering 

Casanellas Mercado, Ignasi (Date of defense: 2022-03-17)

Injuries and conditions of musculoskeletal tissues are among the main causes of disability worldwide and there is a wide need for improved regenerative therapies. In vitro platforms and biomaterials that aim to guide stem ...

Cell-enriched engineered cardiac grafts improve heart function and promote cardiac regeneration: a novel therapy for myocardial infarction 

Perea Gil, Isaac (Date of defense: 2017-07-03)

El infarto de miocardio es una de las enfermedades cardiovasculares de mayor incidencia y mortalidad entre la población mundial. A pesar de los diferentes tratamientos empleados, a día de hoy ninguno de ellos consigue ...

Cell-extrinsic barriers of cellular plasticity: contribution of natural killer cells, T lymphocytes and vitamin B12 to in vivo reprogramming 

Meléndez Esteban, Elena (Date of defense: 2022-03-24)

The ectopic expression of transcription factors Oct4, Sox2, Klf4 and Myc (OSKM) enables the conversion of differentiated cells into pluripotent stem cells, a process known as “reprogramming”. Methods based on in vivo ...

Cell-penetrating peptides as drug shuttles for pain management and other therapeutic applications 

Gallo, María (Date of defense: 2021-07-22)

This thesis focuses on one of the biggest challenges facing drug discovery field: the efficient targeted delivery of therapeutic compounds, and how cell-penetrating peptides (CPPs) acting as drug delivery vectors can ...

Cellular and Molecular Mechanisms of Novel Therapies to Ameliorate Liver Sinusoidal Dysfunction in Cirrhotic Portal Hypertension 

Marrone, Giusi (Date of defense: 2014-06-27)

Increased intrahepatic vascular resistance (IHVR), mainly due to elevated vascular tone together with the maturation of hepatic fibrosis and the drop of the hepatic endothelial function, is the main factor in the development ...

Cellular and Wi-Fi technologies evolution: from complementarity to competition 

Bojovic, Biljana (Date of defense: 2022-01-12)

This PhD thesis has the characteristic to span over a long time because while working on it, I was working as a research engineer at CTTC with highly demanding development duties. This has delayed the deposit more than I ...

Cellular approximations of infinite loop spaces and classifying spaces 

Gavira Romero, Alberto (Date of defense: 2014-02-17)

Dado un espacio topológico punteado A, E. Dror-Farjoun introduce en 1995 la noción de A-homotopía, donde A y sus suspensiones juegan el mismo papel que las esferas en homotopía clásica. Por tanto se definen los grupos de ...

Cellular Ca2+ homeostasis in the pathophysiology of chronic respiratory diseases 

Cantero Recasens, Gerard (Date of defense: 2013-01-10)

Calcium works as a second intracellular messenger in all cell types and its downstream signalling is a key pathway for many systemic functions. In the lungs, the majority of activating stimuli trigger intracellular calcium ...

Cellular dynamics and molecular mechanisms underlying the 3D organization and connectivity of the statoacoustic ganglion 

Bañón González, Aitor (Date of defense: 2023-02-24)

The statoacoustic ganglion (SAG) is a complex 3D structure composed by neurons in charge of transmitting the information from inner ear hair cells to the CNS. During development, SAG copes with otic tissue demands to ...

Cellular immunotherapy for B-cell lymphoma with B-cell lymphoma with NKT-cell agonists 

Escribà Garcia, Laura (Date of defense: 2016-05-27)

Las células NKT representan una pequeña población de linfocitos con especificidad única para antígenos glicolipídicos, presentados por el receptor CD1d presente, principalmente, en las células dendríticas. Estas células ...