Now showing items 5766-5785 of 41446
Maric, Aida (Date of defense: 2021-11-05)
The circadian clock is an endogenously generated timekeeping mechanism that generates 24-hour rhythms in multiple biological processes. The rhythmic oscillations provide an adaptive advantage, allowing organisms to anticipate ...
Moreno González, Eduardo (Date of defense: 2010-06-30)
One of the main issues in animal evolution deal with the transition from radial organisms (Cnidaria and Ctnenophora), with only one axis of symmetry, the Oral-Aboral (OA) axis, to bilateral organism (Bilateria), bearing ...
Amargant i Riera, Farners (Date of defense: 2018-07-19)
The centrosome is an essential organelle for the development of a new organism in animals. Upon fertilization the spermatozoon enters into the oocyte providing its basal body that converts into the first centrosome of the ...
Esteve Codina, Anna (Date of defense: 2012-09-26)
En aquesta tesis, hem estudiat els patrons de variabilidad nucleotídica del genoma del porc per entendre millor quines forces evolutives l’han afectat. El porc domèstic és una espècie domèstica que presenta una gran ...
Stevanović, Irena (Date of defense: 2013-12-04)
We have identified PrimPol, a yet uncharacterized protein that can act in vitro as a low processivity polymerase able to bypasses thymine dimers in DNA. PrimPol localizes to both the nucleus and mitochondria. In order ...
Simões, Inês Tadeu dos Anjos (Date of defense: 2017-09-14)
Our goal in this doctoral thesis was to study the immunomodulatory effects of CD5 and CD6, two proteins expressed on the lymphocytes membrane. These two proteins belong to the Scavenger Receptors Cystein- Rich superfamily, ...
Permanyer Bosser, Marc (Date of defense: 2013-11-08)
La transmissió cèl·lula a cèl·lula del VIH-1 és un mecanisme altament eficient de disseminació viral, i la seva rellevància durant la difusió in vivo en els llocs actius de replicació, és a dir, en els teixits limfoides ...
Plans Pujolràs, Albert (Date of defense: 2017-09-26)
The concrete-steel composite slabs show a complex structural characterization due to the different behaviours at the two materials. The materials are exposed to different deformations, large deflections and complex stresses ...
Nájar Durán, Elena (Date of defense: 2015-11-10)
El déficit hídrico se ha convertido un una gran amenaza hacia la producción agrícola en todo el mundo. La identificación de nuevos actores en la respuesta al estrés por sequía en plantas cultivables es vital para entender ...
Rué Cabré, Laura (Date of defense: 2012-07-12)
La malaltia de Huntington és un trastorn neurodegeneratiu progressiu causat per una expansió de repeticions del triplet CAG (més de 37) en l’exó 1 del gen de la huntingtina que genera una proteïna aberrant. Aquesta proteïna ...
Maceda Porto, Iago (Date of defense: 2021-04-28)
In this work we present a new whole genome sequencing dataset with samples gathered from the Spanish Eastern Pyrenees (SEP) with more than 40x coverage. We apply both classical and new methods to unveil their particular ...
Vicioso Mantis, Marta (Date of defense: 2022-09-27)
The thesis objectives resulted from previous work from Dr Martínez-Balbás lab that characterized the cooperation between TGFβ and JMJD3 to regulate transcription at enhancers, promoters, and gene bodies.Taking into ...
Chen, Weiwei (Date of defense: 2020-11-12)
El rellotge circadià està sincronitzat per senyals mediambientals externes, principalment la llum i la temperatura. Entendre com respon el rellotge circadià de la planta a les oscil·lacions de temperatura és crucial per ...
Fernández Luis, Sheila (Date of defense: 2022-11-21)
[eng] INTRODUCTION Children acquire human immunodeficiency virus (HIV) infection mainly due to vertical transmission (VT) from their mothers, during pregnancy, delivery or breastfeeding (1). Without immediate access to ...
Urdiroz Urricelqui, Uxue (Date of defense: 2022-04-07)
El papel que juega el metabolismo lipídico en la progresión del cáncer está siendo revisado. Estudios recientes de nuestro laboratorio demuestran que el tratamiento con ácido palmítico (AP) de células en cultivo o ...
Cruz Santa Cruz, Tamara (Date of defense: 2017-07-21)
RATIONALE: Chronic obstructive pulmonary disease (COPD) is characterized by chronic airflow limitation caused by a combination of airways disease (bronchiolitis) and parenchymal destruction (emphysema), whose relative ...
Cemeli, Tània (Date of defense: 2019-06-20)
El glioblastoma (GBM) és el tumor més freqüent del sistema nerviós central en adults. Aquesta neoplàsia mostra una elevada capacitat d’evasió migrant cap als teixits circumdants que impossibiliten la resecció quirúrgica ...
Anta Rodríguez, Héctor (Date of defense: 2016-12-15)
Alzheimer’s disease (AD) is the most common type of dementia in the elderly. It is associated to a progressive loss of memory, problems in learning and behaviour changes. This disease is characterized by the accumulation ...
Baptista, Inês do Carmo Viegas (Date of defense: 2022-04-07)
Leukaemia is one of the types of cancer where treatment resistance is prevalent. Better understanding of leukemic cells metabolism opens possibilities for new therapeutic strategies and better prognosis stratification. ...
Sanz de la Garza, María (Date of defense: 2017-05-05)
The beneficial impact of regular physical activity on cardiovascular health is well established. However, the ideal amount of exercise required to provide these benefits is not well defined, with some recent reports showing ...