Now showing items 5766-5785 of 41446

    Characterization of the functional connection between the BROMODOMAIN and EXTRATERMINAL DOMAIN PROTEIN 9 (BET9) and the circadian clock in Arabidopsis thaliana 

    Maric, Aida (Date of defense: 2021-11-05)

    The circadian clock is an endogenously generated timekeeping mechanism that generates 24-hour rhythms in multiple biological processes. The rhythmic oscillations provide an adaptive advantage, allowing organisms to anticipate ...

    Characterization of the Hox patterning genes in acoel flatworms 

    Moreno González, Eduardo (Date of defense: 2010-06-30)

    One of the main issues in animal evolution deal with the transition from radial organisms (Cnidaria and Ctnenophora), with only one axis of symmetry, the Oral-Aboral (OA) axis, to bilateral organism (Bilateria), bearing ...

    Characterization of the human sperm centrosome and its role in (in)fertility 

    Amargant i Riera, Farners (Date of defense: 2018-07-19)

    The centrosome is an essential organelle for the development of a new organism in animals. Upon fertilization the spermatozoon enters into the oocyte providing its basal body that converts into the first centrosome of the ...

    Characterization of the Iberian pig genome and transcriptome using high throughput sequencing 

    Esteve Codina, Anna (Date of defense: 2012-09-26)

    En aquesta tesis, hem estudiat els patrons de variabilidad nucleotídica del genoma del porc per entendre millor quines forces evolutives l’han afectat. El porc domèstic és una espècie domèstica que presenta una gran ...

    Characterization of the in vivo functions of PrimPol, a novel TLS primase-polymerase 

    Stevanović, Irena (Date of defense: 2013-12-04)

    We have identified PrimPol, a yet uncharacterized protein that can act in vitro as a low processivity polymerase able to bypasses thymine dimers in DNA. PrimPol localizes to both the nucleus and mitochondria. In order ...

    Characterization of the in vivo immunomodulatory properties of CD5 and CD6 

    Simões, Inês Tadeu dos Anjos (Date of defense: 2017-09-14)

    Our goal in this doctoral thesis was to study the immunomodulatory effects of CD5 and CD6, two proteins expressed on the lymphocytes membrane. These two proteins belong to the Scavenger Receptors Cystein- Rich superfamily, ...

    Characterization of the infection mechanism during cell-to-cell transmission of HIV-1 

    Permanyer Bosser, Marc (Date of defense: 2013-11-08)

    La transmissió cèl·lula a cèl·lula del VIH-1 és un mecanisme altament eficient de disseminació viral, i la seva rellevància durant la difusió in vivo en els llocs actius de replicació, és a dir, en els teixits limfoides ...

    Characterization of the longitudinal shear strength in composite slabs 

    Plans Pujolràs, Albert (Date of defense: 2017-09-26)

    The concrete-steel composite slabs show a complex structural characterization due to the different behaviours at the two materials. The materials are exposed to different deformations, large deflections and complex stresses ...

    Characterization of the maize protein ZmSTOP1 and its role in drought stress response 

    Nájar Durán, Elena (Date of defense: 2015-11-10)

    El déficit hídrico se ha convertido un una gran amenaza hacia la producción agrícola en todo el mundo. La identificación de nuevos actores en la respuesta al estrés por sequía en plantas cultivables es vital para entender ...

    Characterization of the mechanisms underlying alterations in macroautophagy and survival signalling in Huntington’s disease 

    Rué Cabré, Laura (Date of defense: 2012-07-12)

    La malaltia de Huntington és un trastorn neurodegeneratiu progressiu causat per una expansió de repeticions del triplet CAG (més de 37) en l’exó 1 del gen de la huntingtina que genera una proteïna aberrant. Aquesta proteïna ...

    Characterization of the micro-substructure of a rural population from the Pyrenees from a geodesic and technical point of view using NGS data : Quantification of batch effects in whole genome sequence data 

    Maceda Porto, Iago (Date of defense: 2021-04-28)

    In this work we present a new whole genome sequencing dataset with samples gathered from the Spanish Eastern Pyrenees (SEP) with more than 40x coverage. We apply both classical and new methods to unveil their particular ...

    Characterization of the molecular mechanisms used by JmjC-lysine demethylases to regulate gene expression 

    Vicioso Mantis, Marta (Date of defense: 2022-09-27)

    The thesis objectives resulted from previous work from Dr Martínez-Balbás lab that characterized the cooperation between TGFβ and JMJD3 to regulate transcription at enhancers, promoters, and gene bodies.Taking into ...

    Characterization of the movement of a circadian protein in the temperature-dependent root synchronization of Arabidopsis thaliana 

    Chen, Weiwei (Date of defense: 2020-11-12)

    El rellotge circadià està sincronitzat per senyals mediambientals externes, principalment la llum i la temperatura. Entendre com respon el rellotge circadià de la planta a les oscil·lacions de temperatura és crucial per ...

    Characterization of the prevention and care cascade in children living with HIV in the Manhiça district, Mozambique 

    Fernández Luis, Sheila (Date of defense: 2022-11-21)

    [eng] INTRODUCTION Children acquire human immunodeficiency virus (HIV) infection mainly due to vertical transmission (VT) from their mothers, during pregnancy, delivery or breastfeeding (1). Without immediate access to ...

    Characterization of the proteome and palmitoylome alterations induced by palmitic and oleic acids in OSCC cells 

    Urdiroz Urricelqui, Uxue (Date of defense: 2022-04-07)

    El papel que juega el metabolismo lipídico en la progresión del cáncer está siendo revisado. Estudios recientes de nuestro laboratorio demuestran que el tratamiento con ácido palmítico (AP) de células en cultivo o ...

    Characterization of the pulmonary and systemic immune response in relation with lung stem cells in patients with COPD 

    Cruz Santa Cruz, Tamara (Date of defense: 2017-07-21)

    RATIONALE: Chronic obstructive pulmonary disease (COPD) is characterized by chronic airflow limitation caused by a combination of airways disease (bronchiolitis) and parenchymal destruction (emphysema), whose relative ...

    Characterization of the Role of Cyclin D1 and Ral GTPases in the Proliferation and Dissemination of Glioblastoma 

    Cemeli, Tània (Date of defense: 2019-06-20)

    El glioblastoma (GBM) és el tumor més freqüent del sistema nerviós central en adults. Aquesta neoplàsia mostra una elevada capacitat d’evasió migrant cap als teixits circumdants que impossibiliten la resecció quirúrgica ...

    Characterization of the role of the CPEB family of RNA-binding proteins in neurodegeneration 

    Anta Rodríguez, Héctor (Date of defense: 2016-12-15)

    Alzheimer’s disease (AD) is the most common type of dementia in the elderly. It is associated to a progressive loss of memory, problems in learning and behaviour changes. This disease is characterized by the accumulation ...

    Characterization of the role of TKTL1 in Acute Monocytic Leukaemia 

    Baptista, Inês do Carmo Viegas (Date of defense: 2022-04-07)

    Leukaemia is one of the types of cancer where treatment resistance is prevalent. Better understanding of leukemic cells metabolism opens possibilities for new therapeutic strategies and better prognosis stratification. ...

    Characterization of the spectrum of cardiac adaptation to endurance exercise: Impact of gender and training load 

    Sanz de la Garza, María (Date of defense: 2017-05-05)

    The beneficial impact of regular physical activity on cardiovascular health is well established. However, the ideal amount of exercise required to provide these benefits is not well defined, with some recent reports showing ...