Role of linker Histone H1 variants in cell proliferation, Chromatin Structure and Gene expression in breast cancer cells 

Sancho Medina, Mònica (Date of defense: 2008-05-30)

At least eleven histone H1 variants exist in mammalian somatic cells that bind to the linker DNA and stabilize the nucleosome particle contributing to higher order chromatin compaction. In addition of playing a structural ...