Universitat de Barcelona
Now showing items 8113-8132 of 11103
This thesis is focused in the identification and improvement of lipases for biotechnological application. The importance of lipases is increasing in several industries. However, the commercial use of lipases is still a ...
Local invasion is a key cell-biological event in the metastatic cascade. In response to a changing microenvironment, cancer cells may act using two main strategies of invasion: single cell invasion and collective invasion. ...
The increase in water use efficiency in order to maintain or improve crop yields in times of global warming and progressive reduction of water resources is one of the major challenges faced by agricultural sciences in the ...
An alternative allowing diene-derivatised polyamides to be used in Diels-Alder conjugation reactions has been explored and developed. In this methodology, conjugation takes place between a fully protected, resin-linked ...
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are clinically distinct neurodegenerative diseases that are connected by genetic and pathological overlap. ALS patients present with muscle ...
Alzheimer’s disease (AD) is the main neurodegenerative disorder and one of the most important health-care problems worldwide, because of its high prevalence and personal and economic impact. To aggravate this situation, ...
[eng] Chronic liver diseases are one of the most prevalent diseases worldwide. The study of the signaling pathways involved in the fibrogenic process as well as the evaluation of novel therapies such as nanoparticles (NPs) ...
Cereals are the basis of the normal diet in most Mediterranean countries and it is estimated that they account for 35-50% of the regional populations’ dietary energy consumption. Water deficit is the main constraint limiting ...
Diabetes represents one of the biggest health challenges of the 21st century. Insulin resistance is the primary defect in the most common form of diabetes, type 2 diabetes mellitus (T2D), and is defined as a failure in the ...
The aim of this thesis was to study quantum phenomena and excitation modes in type-I superconductors and magnetic vortices. The intermediate state in type-I superconductors is characterized by the gradual penetration ...
Quatsomes are lipid-based nanovesicles developed by Nanomol group, composed of ionic surfactants and sterol derivatives. Regarding their properties, Quatsomes have shown to be highly homogenous and stable for years, important ...
AMPA receptors (AMPARs) are responsible for the 90% of synaptic transmission and are involved in plasticity, developmental and neurological processes. Their function depends on the proteins interacting with the AMPAR ...
c-Src is a central player in several cellular signaling pathways. It controls impor- tant cellular processes like cellular proliferation, survival or motility. Therefore, a number of tumoral diseases have been related to ...
Obesity is the most common metabolic disorder that have alarmingly increased all over the world in the last few decades. The hormone insulin is one of the major endocrine axis deregulated in obesity and will be the focus ...
The microtubule cytoskeleton plays essential roles during cell division, migration, differentiation, defining cell morphology and organizing intracellular transport. The properties of microtubules, such as their stability, ...
Force plays an essential role in all fields of biology. Measurement of these forces with high precision provides information about the structure, dynamics, intra and intermolecular interactions, and the mechanical properties ...
The indiscriminate and/or improper use of veterinary drugs is the cause of potential adverse health effects due to the risk of entering into the food chain and the appearance of residues in food products of animal origin. ...
Head and neck squamous cell carcinoma (HNSCC) is usually diagnosed in advanced stages. The treatment has not changed much on the last decades, being limited to surgery followed by radiotherapy and/or chemotherapy [mainly ...
The present thesis is included in the area of Nanomedicine and supramolecular chemistry, focused on the design and preparation of different nano and microtools for delivery, therapy and sensing. Initially, the synthesis ...
La novel·la històrica protagonitza el procés de represa de la novel·la catalana durant la Renaixença, que es desenvolupa en dues etapes: la primera, en els anys seixanta, d'escassa producció, mentre en la segona, en els ...
