Now showing items 4853-4872 of 11066

    Exploring Food System Transformations in Spain (1980-2021) 

    Parajuá Carpintero, Noelia (Date of defense: 2023-12-20)

    [eng] In this PhD Thesis, I examine the transformations of the Spanish food system from 1980 to the present, focusing on its socioeconomic structural changes and their impacts on sustainability and social equity. My research ...

    Exploring heterocyclic scaffolds in the development of multi-target anti-Alzheimer and multi-trypanosomatid compounds 

    Di Pietro, Ornella (Date of defense: 2015-11-06)

    The aim of this PhD thesis consists of the synergistic combination of both highly efficient synthetic approaches and molecular modelling tools for the structure-based drug design and synthesis of novel bioactive heterocyclic ...

    Exploring lifelong learning motivational ecologies through the narratives of senior language users 

    Darnault, Bérénice (Date of defense: 2023-07-11)

    [eng] In the context of an ageing and increasingly more independent learning population, a narrative inquiry into the life stories of highly motivated senior language users remains a promising yet relatively unexplored ...

    Exploring molecular mechanisms of key targets in metabolic and infectious diseases 

    Aledavood, Elnaz (Date of defense: 2021-10-01)

    This doctoral thesis is focused on disclosing molecular factors that regulate the functional mechanism of key targets in i) metabolic disorders, such as diabetes and obesity, and ii) tuberculosis (TB). These diseases have ...

    Exploring protein structure changes due to somatic mutations in cancer 

    Diéguez Docampo, Andrea (Date of defense: 2023-03-02)

    [eng] Cancer is one of the most common diseases worldwide. Despite that a lot of time and resources have already been spent in this topic, there is still a long way to go to be able to cure every patient and improve their ...

    Exploring Signatures of New Physics in Cosmology 

    Bellomo, Nicola (Date of defense: 2020-01-24)

    Cosmology is the study of the origin and evolution of our Universe as a whole. Even if the theoretical framework of Cosmology was developed a century ago, with the formulation of General Relativity by Albert Einstein, it ...

    Exploring structure-function relationship of the mitochondrial DNA packaging protein Abf2p and its dialogue with the DNA 

    Chakraborty, Arka (Date of defense: 2016-07-08)

    Mitochondria are intracellular double-membrane bound organelles in eukaryotic cells that act as the major suppliers of adenosine triphosphate (ATP). They possess their own DNA (mtDNA) that codes for components of the ...

    Exploring T-DNA gene mechanisms and optimizing centelloside production in Centella asiatica hairy root cultures 

    Alcalde Alvites, Miguel Angel (Date of defense: 2023-12-19)

    [eng] Plant biofactories constitute an eco-friendly alternative to chemical synthesis as they have a lower environmental impact and therefore contribute to a more sustainable future. Hairy root cultures, generated by ...

    Exploring the heavy atom effect and supramolecular assemblies of Au(I) and Pt(II) complexes 

    Romo Islas, Guillermo (Date of defense: 2023-07-14)

    [eng] This thesis is mainly focused on studying the photophysical properties of Au(I), Ag(I), Cu(I), and Pt(II) coordinated compounds. This work can be divided into two parts: on the one hand, the compounds of the group ...

    Exploring the regulation and function of TIGAR in cancer cells 

    Simon Molas, Helga (Date of defense: 2019-07-05)

    The TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) gene was described in 2006 by Dr. Karen Vousden's group in response to the induction of the tumour suppressor gene p53. Since then, numerous studies have focused ...

    Exploring the role of NR2E3 in photoreceptor cell fate determination 

    Aísa Marín, Izarbe (Date of defense: 2022-05-13)

    The transcription factor NR2E3 participates in photoreceptor cell fate determination as it functions as both transcriptional repressor of cone genes and activator of rod genes. Mutations in NR2E3 cause retinitis pigmentosa ...

    Exploring the Role of Third Party Logistic (TPL) Companies as Enablers for Collaborative Systems and Blue Ocean Strategy in Supply Chain Management 

    Hargous Pretel, Bernardo Andrés (Date of defense: 2023-11-10)

    [eng] This doctoral thesis investigates the potential of third-party logistics (TPL) companies as key facilitators of collaborative systems and the implementation of the blue ocean strategy within the realm of supply chain ...

    Exploring the Universe with Quasar Absorption Spectra: correlations among tracers of the mass density field and the impact of ionizing background intensity fluctuations 

    Gontcho, Satya Gontcho A (Date of defense: 2017-09-22)

    The work we present in this manuscript revolves around the use of quasar spectra to probe the Universe. Absorption features in the electromagnetic spectrum of bright distant quasars by ionized hydrogen give us access to ...

    Exploring what disruptive innovation is and its influence on Spanish incumbents 

    Martínez Vergara, Sucet Jimena (Date of defense: 2021-06-14)

    Disruptive innovation has become one of the most renowned types of innovation in the business world. The results of the preliminary review of the literature on this theory have revealed interesting questions about how ...

    Explotación abusiva de una posición dominante, La. 

    Pellisé Capell, Jaume (Date of defense: 1996-01-11)

    Los artículos 82 TCE (antes 86 TCE) y 6 LEDC prohíben la explotación abusiva de una posición dominante en el mercado; sin embargo no definen los importantes términos típicos que contienen. Este trabajo se dedica al estudio ...

    Exportación e importación en y desde el Mediterráneo en la Baja Edad Media. Mercaderes, mercancías y rutas comerciales (1349-1450) 

    Polonio Luque, Gloria (Date of defense: 2012-04-18)

    Comercio y Mediterráneo son dos puntos clave dentro de la historia de la Baja Edad Media, por lo que esta tesis doctoral titulada “Exportación e importación en y desde el Mediterráneo en la Baja Edad Media. Mercaderes, ...

    Exposición al humo ambiental del tabaco y medidas de control del tabaquismo 

    Martínez Sánchez, José M. (Date of defense: 2010-12-10)

    Antecedentes: En España, hasta 3.200 defunciones anuales son atribuidas al tabaquismo pasivo. La exposición al humo ambiental del tabaco (HAT) aumenta el riesgo de padecer enfermedades crónicas como cáncer de pulmón, ...

    Exposición intermitente a altitud simulada y ejercicio para la recuperación del daño muscular: células madre circulantes y ajustes hemorreológicos en ratas entrenadas 

    Núñez Espinosa, Cristian (Date of defense: 2015-04-09)

    La hipótesis general de este trabajo se basa en que un protocolo de hipoxia hipobárica intermitente (IHH) combinada con ejercicio aeróbico ligero en normoxia, puede tener un efecto beneficioso en la regeneración de musculatura ...

    Exposure characterisation and sources of nanoparticles in workplace environments 

    Godinho da Fonseca, Ana Sofia (Date of defense: 2016-06-06)

    Exposure to micro- and nano-scaled particles has been widely linked to adverse health effects including pulmonary, cardiovascular and nervous system disease leading to increased mortality and morbidity rates. With regard ...

    Expresiones idiomáticas con בבל/ בל (lev y levav) ("corazón") en la Biblia Hebrea y sus implicaciones en la traducción del castellano a las lenguas indígenas de América 

    Liriano Hernández, Fausto Fermín (Date of defense: 2018-11-23)

    El fenómeno de las expresiones idiomáticas es tan antiguo como nuestros registros del lenguaje, es común en todas las lenguas y surge como parte de la necesidad sociolingüística de crear códigos que sean auténticos a cada ...