Lorente Crivillé, Adriana (Date of defense: 2014-07-18)
Natural products from terrestrial plants and microorganisms have long been a traditional source of drugs. For centuries humans have been looking on their environment for medicines to treat illnesses. ...
Farrera Sinfreu, Josep Maria (Date of defense: 2006-07-19)
Les molècules ramificades poden jugar un paper clau en la síntesi en fase sòlida de compostos amb una elevada complexitat estructural. En aquest sentit i concretament en la síntesi de pèptids i ...
Mendive Tapia, Lorena (Date of defense: 2017-02-17)
In the present thesis we have investigated the development of new methodologies for the selective and straightforward chemical modification of Trp amino acid either alone or in peptides. In the first ...
Rocas Alonso, Pau (Date of defense: 2016-02-25)
This thesis, entitled "Multifunctional Self-stratified Polyurethane-Polyurea Nanosystems for Smart Drug Delivery" is structured as a compendium of publications, being organized around a methodological ...
Paradís Bas, Marta (Date of defense: 2015-05-15)
The known as "difficult peptides", as well as those sequences that aggregate in solution, are some of those molecules with high applicability as nanomaterials or even in medicine field. This thesis has ...
Just Baringo, Xavier (Date of defense: 2013-11-25)
The present doctoral thesis has been devoted to the development of a new synthetic strategy to obtain a new member of the thiopeptide, or thiazolyl peptide, family of antibiotics. This new member, ...
Isidro Llobet, Albert (Date of defense: 2008-05-13)
The increasing importance of peptides as drugs creates the necessity of new methodologies for the synthesis of complex peptides. This PhD thesis has been focused on the development of new protecting ...
Palà Pujadas, Judith (Date of defense: 2018-03-12)
Chemical protein synthesis has become a potent tool for the synthesis of proteins, especially those which are not easily accessed by DNA recombinant methods, such as proteins with posttranslational ...
Fransen, Peter (Date of defense: 2013-12-05)
Dendrimers are a class of globular highly branched macromolecules with precise architecture. They consist of a multivalent surface with functional group, a core unit where branching starts, and the ...
Subirós Funosas, Ramon (Date of defense: 2011-07-21)
Els pèptids són biopolímers naturals amb una importància cabdal en el cos humà, actuant com a neurotransmissors, endorfines o hormones. Recentment, s’han descobert propietats molt interessants de pèptids ...