Banjer, Hamsa Jameel (Date of defense: 2018-07-06)
Transportome alterations have been associated with oncogenesis. The loss of human Concentrative Nucleoside Transporter 1 (hCNT1) during carcinogenesis seems to be a relatively common event in tumors and ...
Arimany Nardi, Cristina (Date of defense: 2013-12-03)
Nucleoside-derived drugs are used for the treatment of haematological malignancies, viral infections and autoimmune or inflammatory diseases. These drugs require membrane transporters to be internalised ...
Grañé Boladeras, Natàlia (Date of defense: 2012-12-21)
hENT2 is the human nucleoside transporter for which most splice variants have been described to date, in contrast to hENT1 for which no variants have been reported yet. In this dissertation, we have ...