Mostrando ítems 1-10 de 11
Rey Carrizo, Matías (Fecha de defensa: 2014-11-28)
Influenza is a major health problem worldwide, as the periodic pandemics of the 20th century have highlighted. Some countermeasures have been developed and have indeed diminish the devastating effects ...
Ayats Rius, Carles (Fecha de defensa: 2007-06-08)
Els compostos policíclics d'elevada simetria, a més del seu gran atractiu estètic i interès estructural, són substrats valuosos per a estudis mecanístics o bé com a intermedis en la síntesi de molècules ...
Torres Costa, Eva (Fecha de defensa: 2013-09-30)
Research for new antivirals to treat Influenza A virus infections has gained importance during this last decade due to the imminent danger of an Influenza pandemic. For some years, several new strains ...
Bagán Polonio, Andrea (Fecha de defensa: 2022-09-23)
The synthesis of heterocyclic organic compounds allows access to a wide arsenal of compounds with potential pharmacological activity. This Thesis is part of the field of pharmaceutical chemistry, ...
Barniol Xicota, Marta (Fecha de defensa: 2017-01-13)
L’objectiu de la present tesi doctoral consisteix en desenvolupar molècules policícliques de baix pes molecular que tinguin com a diana tres canals iònics específics: la viroporina A/M2 del virus de la ...
Muñoz Blasco, Mª Rosa (Fecha de defensa: 2007-01-26)
Como continuación de los estudios realizados previamente por el grupo de investigación en el campo de los alquenos piramidalizados, en la presente Tesis Doctoral se ha realizado un estudio de generación, ...
Valverde Murillo, Elena (Fecha de defensa: 2015-10-30)
For over eighty years, adamantane ring has interested organic chemists for its simplicity and symmetry. The rigid tricyclo[3.3.1.13,7]decane skeleton has provided a unique structural template for ...
Leiva Martínez, Rosana (Fecha de defensa: 2017-09-22)
The present PhD Thesis evolves around the design, synthesis and pharmacological evaluation of novel 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors. Given that the enzyme active site ...
Codony Gisbert, Sandra (Fecha de defensa: 2020-09-17)
Epoxieicosatrienoic acids acids (EETs) are endogenous chemical mediators derived from arachidonic acid that show anti-inflammatory, antihypertensive, analgesic, angiogenic and antiatherosclerotic effects. ...
Jora, Beatrice Elena (Fecha de defensa: 2022-10-27)
[eng] The present thesis focuses on the study and synthesis of three active principles (APIs) with therapeutic activity. Although these compounds are commercially available, their route of synthesis are ...