Hyperactivation of the TGF-β signaling pathway in glioblastoma: mechanisms and consequences 

Rodón Ahnert, Laura (Date of defense: 2012-11-28)

The TGF-β pathway is currently considered a therapeutic target in advanced tumors, including glioblastoma (GBM), and several anti-TGFβ agents are in clinical trials and have shown promising results .A thorough understanding ...