López Pelegrín, Maria del Mar (Date of defense: 2015-11-13)
Metallopeptidases are major players in the physiology and pathology of all living organisms. Their exquisite regulation is therefore essential for proper function and to prevent misdirected temporal ...
Amo Maestro, Laura del (Date of defense: 2021-06-11)
The present thesis has established a new and state of the art mammalian protein expression system at the laboratory which has then contributed with high-yield expression for the purification and ...
Kaczmarska, Zuzanna (Date of defense: 2014-12-05)
Picornaviridae are among the most diverse and oldest known viral families that include many important pathogens of humans and animals. They are small, icosahedral (+)ssRNA viruses, causing a variety of ...
dos Reis Mendes, Soraia Inês (Date of defense: 2022-10-28)
[eng] Several proteases and their antagonistic protein or peptide inhibitors sparked researchers’ interest due to their potential as therapeutic targets. The present thesis, which compiles results ...