New roles for Snail1 -expressing CAF during primary tumor progression and secondary niche colonization 

Olivera-Salguero, Rubén (Date of defense: 2019-07-19)

Snail1 is the master regulator of the Epithelial-to-Mesenchymal Transition (EMT) and is also crucial for fibroblast activation upon TGFβ signaling. In cancer, Snail1 expression in primary tumors correlates with the appearance ...