Ortet Cortada, Laura (Date of defense: 2010-06-04)
We have identified a novel Cyclin, called Cyclin O, which is able to bind and activate Cdk2 in response to intrinsic apoptotic stimuli. We have focused on the study of Cyclin Oα and Cyclin Oβ, ...
Blanco Ares, Gonzalo (Date of defense: 2017-12-01)
The analysis of the microenvironment in CLL-like monoclonal B cell lymphocytosis (MBL) and early-stage chronic lymphocytic leukemia (CLL) is relevant for understanding the natural history of CLL. To ...
Johnsen, Lisa (Date of defense: 2016-12-18)
Epithelial tissues undergo extensive remodeling during embryonic development. Recent studies have revealed that, in a number of developmental processes, epithelial remodeling is associated with pulsations ...
Di Vona, Chiara (Date of defense: 2013-09-20)
The view on how protein kinases regulate gene expression have recently expanded to include not only transcription factors but also histones, chromatin remodelers or components of the basal transcription ...
Thuer, Ernst (Date of defense: 2017-09-22)
This thesis describes the application of Next Generation Sequencing, especially RNA sequencing, on the investigation of the pathogenic yeast Candida parapsilosis. Pathogenic yeasts of the Candida clade ...
Gálvez García, Héctor (Date of defense: 2017-01-20)
The vertebrate inner ear is the organ responsible for the senses of balance, acceleration and audition. Three cell types form the functional unit of the ear: hair cells, neurons and supporting cells. ...
Wallrapp, Frank (Date of defense: 2011-04-04)
El objetivo de esta tesis se centra en el estudio de la transferencia de electrones (ET), una de las reacciones más simples y cruciales en bioquímica. Para dichos procesos, ...
Vanneste, David (Date of defense: 2010-09-21)
During cell division, a macromolecular machine is assembled to segregate the two sets of chromosomes carrying the genetic material into the two daughter cells. This machine, the mitotic spindle, is a ...
Bruns, Caroline (Date of defense: 2013-04-30)
A part de la secreció convencional, en la qual les proteïnes són transportades a través del reticle endoplasmàtic (RE) i de l'aparell de Golgi, s'han descrit, per a diferents proteïnes i en organismes ...
Herráiz Yebes, Alba (Date of defense: 2014-01-31)
In the present thesis we studied the effects of hydric stress in the ovary of the cockroach Blattella germanica. At morphological level, we described ovarian resorption induced by water deprivation. At ...