Balducci, Elisa (Date of defense: 2012-02-24)
Cerebral cortex is essential to exert the highest functions in mammals. Understanding the developmental processes that underlie the generation and functionality of cortical cell populations represents ...
Najas Sales, Sònia (Date of defense: 2014-10-10)
In this work we have assessed the possible contribution of the human chromosome-21 gene DYRK1A in the developmental cortical alterations associated with Down Syndrome using the mBACTgDyrk1a mouse, which ...
Laguna Tuset, Ariadna (Date of defense: 2008-12-18)
El gen DYRK1A es troba situat en una regió del cromosoma 21 humà que s'ha associat a alteracions en el neurodesenvolupament. Aquest treball mostra com canvis en la dosis gènica de Dyrk1A en el ratolí ...