Now showing items 21-31 of 31
Vila Vadrí, Jordi (Date of defense: 2023-04-21)
The development of novel catalytic methodologies involving the formation of carbon – carbon/heteroatom bonds to produce cyclic systems constitutes a field of great interest in the modern synthetic organic chemistry. Over ...
Planas i Grabuleda, Marta (Date of defense: 1996-03-15)
Spiro-γ-lactones are widely distributed among natural products, several of them being well known by their interesting biological activities. We describe herein the synthesis of 1-oxaspiro[4.4]nonan derivatives and ...
Cerezo Frias, Vanessa (Date of defense: 2009-05-28)
Els aminoàcids biarílics es troben en una àmplia varietat de pèptids naturals amb important activitat biològica. Concretament, les arilhistidines formen part de les aciculitines, pèptids amb activitat citotòxica i antifúngica, ...
Oliveras Rovira, Àngel (Date of defense: 2020-10-27)
Nowadays, around a third of the agricultural production is lost due to the damage caused by pests, resulting in a significant economic impact. It is estimated that about a third of these losses are provoked by phytopathogens. ...
Mejias Ruiz, Francesc Xavier (Date of defense: 2010-06-04)
La tesis doctoral está dividida en 3 partes:<br/>La primera presenta la aplicación del grupo TCP a la síntesis de PNAs en fase sólida. La segunda está dedicada a la síntesis de un nuevo tipo de nucleoaminácido para la ...
Font Gimbernat, David (Date of defense: 2003-12-09)
En aquest treball s'ha desenvolupat una metodologia eficaç envers la síntesi de diferents derivats pirimidínics amb un alt grau de diversitat molecular. Aquesta metodologia es basa en la S-alquilació selectiva dels ...
Ng Choi, I-teng Montserrat (Date of defense: 2015-12-15)
The incorporation of unsymmetrical biaryl systems into peptide sequences is a strategy that can improve their biological activity. Due to the difficulty of arylating the 4(5}-position of the imidazole ring, this doctoral ...
Rosés Subirós, Cristina (Date of defense: 2016-01-22)
This thesis is focused on the development of synthetic approaches to obtain new bioactive peptides. The first part deals with the design of new antimicrobial peptide/cell-penetrating peptide conjugates as anticancer agents. ...
Güell Costa, Imma (Date of defense: 2012-01-27)
In the present PhD thesis we studied the solid-phase peptide synthesis of antimicrobial peptides derived from the lead peptides BP100 and BPC194. First, peptides derived from BP100 containing D-amino acids at different ...
El Marrouni El Ghazaoui, Abdellatif (Date of defense: 2012-04-13)
The principle theme of this thesis was the synthesis of bioactive compounds. To this end, this work was focus on two main projects. The first one, which was carried out in the Department of Chemistry of the University of ...
Parera Briansó, Magda (Date of defense: 2014-05-20)
The transition-metal catalysed [2+2+2] cycloaddition reaction is a highly efficient synthetic tool that allows six-membered polysubstituted carbo- and heterocyclic derivatives to be obtained in an atom economy process. ...