Mechanisms of invasion and metastasis in colorectal cancer 

    García de Albéniz, Xabier (Date of defense: 2015-04-15)

    We studied the mechanisms driving the metastatic spread in colorectal cancer (CRC), focusing in the MAPK pathway. We developed in vivo a highly metastatic cell line using a KRAS-mutated cell line (SW620) in an ortothopic ...