Anusha, Koneti (Date of defense: 2015-10-02)
Mitochondria dysfunction is documented in the substantia nigra in Parkinson's disease (PD), a region which plays a central role in the characteristic motor manifestations of the disease. Mitochondria! ...
Szczesna, Karolina (Date of defense: 2014-09-26)
INTRODUCTION: In 1966, Rett syndrome (RTT, OMIM#312750) was for the first time described as a clinical issue by Dr. Andreas Rett, an Austrian pediatrician. He has observed in 22 patients similar ...
Rabaneda Lombarte, Neus (Date of defense: 2019-07-22)
Neuroinflammation is present in practically all neurological disorders. Microglial cells, the main representatives of the endogenous immune system of the brain, play a key role in neuroinflammation, ...
Pérez Salvia, Montserrat (Date of defense: 2019-03-01)
Cancer is considered nowadays a genetic and epigenetic disease. Aberrancies in epigenetic marks in DNA and histone tails together with alterations in epigenetic regulators responsible of catalyzing ...
Lucariello, Mario (Date of defense: 2017-03-16)
STUDY I HYPOTHESIS Genetic alterations have already been recognized as major etiological factors for ASD and ID, of which RTT is an example. In addition to the contribution of polymorphic variants ...
Bernabeu Aznar, Maria (Date of defense: 2013-06-14)
P. vivax is the most widespread malaria, it accounts for 25-40% of the global disease burden and it is estimated that causes from 132 to 391 million clinical cases each year. It is amply accepted that ...
Rebollo González, Beatriz (Date of defense: 2017-06-14)
The cerebral cortex is organized in complex circuits of neurons strongly interconnected in a conductive medium. During deep sleep stage, this neuronal connectivity generates recurrent synchronized ...
Sauchelli Toran, Sarah (Date of defense: 2016-12-19)
There is an increasing worldwide prevalence of obesity and anorexia nervosa. These conditions are having important health consequences. Among the numerous factors linked to these extreme weight conditions, ...
Gomila Grange, Aina (Date of defense: 2018-12-18)
Surgical site infections (SSI) are currently the most frequent healthcare-associated infections in Spain and Europe. Its development increases morbidity and mortality of patients and costs of healthcare ...
Moreno Monasterio, Marta (Date of defense: 2015-02-18)
The main goal of this PhD thesis was to understand the mechanisms underlying GBM tumor formation and progression, with a special emphasis on the study of factors that have a role in normal NSC biology, ...
616 - Pathology. Clinical medicine (42)
616.8 - Neurology. Neuropathology. Nervous system (22)
616.9 - Communicable diseases. Infectious and contagious diseases, fevers (16)
616.4 - Pathology of the lymphatic system, haemopoietic (haematopoietic) organs, endocrines (9)
577 - Material bases of life. Biochemistry. Molecular biology. Biophysics (7)