Pedrosa, Leire (Date of defense: 2020-10-30)
[cat] El glioblastoma (GBM) és el tumor primari cerebral més freqüent i més agressiu. Els pacients amb GBM tenen una supervivència mitjana de 15 mesos. Una dels principals dificultats que presenten els ...
Aparicio García, María (Date of defense: 2020-12-09)
[eng] The arrival of antiangiogenic therapies represented a huge advance in the treatment of different tumors, such as renal carcinoma. However, despite initial good results, some tumors were able to ...
Gonçalves Alves, Eliana Carolina (Date of defense: 2021-01-15)
[eng] Neuroblastoma (NB) is the most common extracranial solid childhood tumour. Its clinical and histological manifestations range from benign tumours that spontaneously regress to highly aggressive ...
Caballero Díaz, Daniel (Date of defense: 2018-02-09)
Hepatocellular Carcinoma (HCC) is one of the most common cancers. During hepatocarcinogenesis (a multistep process) there is a disruption of the balance between cell death and survival signalling pathways, ...
Galindo Moreno, Javier Jesús (Date of defense: 2015-04-25)
La apoptosis es un proceso biológico fuertemente conservado a lo largo de la evolución que consta de un sistema de regulación complejo en el que intervienen gran cantidad de proteínas, en su mayoría ...
Figuerola Bou, Elisabet (Date of defense: 2019-12-05)
Ewing sarcoma (ES) is a highly aggressive tumour of the bone and soft tissue that typically affects children, adolescents, and young adults. The fusion protein EWSR1‐FLI1 is the main genetic alteration ...
Serra Navarro, Berta (Date of defense: 2018-07-13)
La regulación y potenciación de la proliferación de la célula β pancreática es un objetivo principal en la prevención y/o retardo de la diabetes. Su replicación se regula a través de un proceso dinámico, ...
Siles Mena, Laura (Date of defense: 2017-06-01)
ZEB1 is a transcription factor best known for its role in cancer progression and metastasis. It is also expressed during embryonic development of different tissues although its function and mechanism ...