Martínez Gutiérrez, Alfredo (Date of defense: 2019-12-13)
One of the main causal factors of skin aging is ultraviolet radiation as part of sun exposure. This radiation induces many changes at the molecular level that alter the proper function of skin biological ...
Martí Sánchez, Laura (Date of defense: 2020-12-18)
Esta tesis es el resultado de un proyecto multicéntrico y traslacional en pacientes pediátricos con trastornos del movimiento y alteraciones en los ganglios basales, centrándose en la parte bioquímica ...
Torra Massana, Marc (Date of defense: 2019-07-10)
La ICSI és una tècnica de reproducció assistida molt eficient, però la fallada de fecundació (FF) pot ocórrer en un 1-3% dels cicles. La FF té un elevat impacte en els pacients i és molt difícil de ...
Duran Ferrer, Martí (Date of defense: 2020-11-19)
The DNA from our cells carries the genetic information to build a human being. This information is interpreted through epigenetic marks that lead to tightly coordinated and cell type-specific gene ...
Cárdenas Brito, Sonia Janneth (Date of defense: 2016-10-26)
El sistema de complemento es parte fundamental de la inmunidad innata, actúa reconociendo patrones moleculares asociados a microorganismos y patógenos, provenientes de ambiente extracelular. Su función ...
Rodrigo Torres, Daniel (Date of defense: 2016-02-05)
La malaltia hepàtica per consum d'alcohol és una hepatopatia crònica amb alta taxa de mortalitat. Aquests pacients poden presentar episodis d'hepatitis alcohòlica (HA), caracteritzats histològicament ...
Pajares García, Sonia (Date of defense: 2016-10-03)
En esta tesis se estudian dos aspectos, el desarrollo de herramientas diagnósticas y terapéuticas aplicado a dos enfermedades metabólicas hereditarias: la deficiencia del transportador de creatina (CRTR) ...
Nadeu Prat, Ferran (Date of defense: 2020-09-23)
Chronic lymphocytic leukemia (CLL) is the most common form of adult leukemia in Western countries. Although the disease might follow an indolent course, it rapidly progresses in a fraction of cases, ...
Barrios Barri, Oriol de (Date of defense: 2017-02-03)
The members of ZEB family of transcription factors (ZEB1 and ZEB2) are widely known for its role in epithelial-to-mesenchymal transition (EMT), a highly relevant process during development and tumor ...
González Tarragó, Víctor (Date of defense: 2019-07-11)
This thesis is a study on the integrin-mediated mechanoresponse by binding partners and force loading rates. Regarding the binding partners, here we demonstrate an alternative and counter-intuitive ...