Soy Platero, Judit (Date of defense: 2014-07-17)
Arabidopsis thaliana seedling growth and development is influenced by both external (such as light and temperature) and internal (like hormones or circadian clock) factors. In short-day (SD) growing ...
Valdivieso Muñoz, Alejandro (Date of defense: 2020-03-05)
In many organisms, sex is determined by a combination of genetic and environmental influences. Epigenetic regulatory mechanisms such as DNA methylation integrate both types of influences. However, ...
Dámaso Riquelme, Estela (Date of defense: 2018-11-09)
La deficiencia reparadora es una característica de los tumores de individuos con síndrome de Lynch, los cuales son portadores de mutaciones o epimutaciones en línea germinal de los genes reparadores de ...
Rodríguez Vaello, Victoria Eugenia (Date of defense: 2020-12-11)
A fundamental step in embryo development is the transition through pluripotency. There are two known sequential states of pluripotency termed naïve and primed pluripotency. Considerable efforts have ...
Louzao Boado, Ánxela (Date of defense: 2019-04-30)
Genetically tractable models such as Drosophila melanogaster may help to identify new approaches to halt malignant growth. During my doctoral thesis, I performed a screen to find mitochondrial genes ...
Olival T., Jonathan F. (Date of defense: 2022-10-20)
[eng] Neonatal arterial ischemic stroke (NAIS) is a cerebrovascular disease that shows a focal disruption of cerebral blood flow due to artery obstruction. Due to its early onset, it can cause long-lasting ...
Norris, Richard (Date of defense: 2021-10-13)
Insulinomas are extremely rare pancreatic neuroendocrine (PNET) tumours that develop from the β-cells of the pancreas.β-cells are the only cells capable of producing the hormine insulin, and play a major ...
Ferrer Aparicio, Silvia (Date of defense: 2018-10-18)
Els trastorns neuromusculars pediàtrics són malalties minoritàries causades per un gran nombre de gens, molts d’ells de gran mida i d’estructura complexa, fet que dificulta enormement el diagnòstic ...
Calucho Prim, Maite (Date of defense: 2021-11-24)
La Fibrosis Quística (FQ) es una enfermedad autosómica recesiva que ocurre cuando existen variantes patogénicas bialélicas en el gen Cystic Fibrosis Transembrane Regulator (CFTR), y que codifica por una ...
Gracia Latorre, Elena (Date of defense: 2023-06-01)
[eng] Enhancers are the master regulators of gene expression. Genes rely on them to be differentially expressed in different tissues, developmental time points or contexts. In recent years, it has been ...