Mostrando ítems 192-211 de 315
Bargalló, Manel Enric (Fecha de defensa: 2020-07-31)
[spa] De entre las vacunas de ácidos nucleicos, las basadas en ARNm autoreplicativos (replicones) o ARNm convencionales unidos a diferentes nanopartículas (NPs) como: oro (Au-NP), nanocápsulas (NCs), ácido poliláctico ...
Sánchez-López, E. (Elena) (Fecha de defensa: 2017-09-21)
The incidence of neurodegenerative diseases, such as Alzheimer's disease, increases every year due to population aging. Therefore, the development of new therapeutic strategies, such as biodegradable nanostructured systems ...
Folle, Camila (Fecha de defensa: 2021-11-26)
The skin is major organ of the human body, and its function is to protect the internal tissue from environmental changes, maintains the body temperature and avoid penetration of contaminants. Therefore, the skin barrier ...
Montero Martín, Sara (Fecha de defensa: 2021-11-22)
Despite the latest advances in early diagnosis and increased resources employed to develop new therapeutic options, effective control of cancer disease remains a challenge. In fact, cancer is the second leading cause of ...
Fanlo Escudero, Lucía (Fecha de defensa: 2019-12-18)
Neuroblastoma (NB) is a devastating paediatric cancer that originates in the developing sympathetic nervous system. These tumours account for 40% of the cases of cancer diagnosed during the first year of life and 8% of the ...
Baelo Álvarez, Aida (Fecha de defensa: 2021-01-28)
Bacterial infections are a major health concern worldwide due to the mortality and comorbidity associated levels. Besides the development of drug-resistance mechanisms, most recalcitrant infections are caused by bacteria ...
Lalaleo Córdova, Liliana Paulina (Fecha de defensa: 2017-03-03)
Linum album is an herbaceous plant with medical interest due to its content of podophyllotoxin (PTOX), an aryltetralin lignan with cytotoxic activity. The study of biotechnological alternatives has generated big interest. ...
Sanchis Villariz, Ana (Fecha de defensa: 2018-07-25)
The central topic of this thesis has been the study, development and validation of diverse multiplexed diagnostics platforms and techniques that can be applied to a wide range of topics, from environmental monitoring to ...
Benítez, Sandra (Fecha de defensa: 2021-01-13)
Receptor activator of nuclear factor kappa-β ligand (RANKL) and its receptor RANK are key mediators of bone resorption1,2. RANKL, its receptor RANK and its natural decoy receptor OPG, which is a competitive inhibitor that ...
Marhuenda Muñoz, María (Fecha de defensa: 2022-09-08)
[eng] The present dissertation aims at broadening current knowledge regarding the importance of bodily or tissue status of bioactive compounds that are highly abundant in the Mediterranean diet (carotenoids and polyphenols) ...
Hidalgo Martínez, Diego Alberto (Fecha de defensa: 2017-07-10)
The thesis is presented as a compendium of publications and includes six different sections: General Introduction, Objectives, Results, General Discussion, Conclusions and References. The General Introduction summarizes ...
Pérez Matas, Edgar (Fecha de defensa: 2023-12-19)
[eng] Plant specialized metabolism is the source of a wide range of bioactive compounds, some of which with relevant pharmacological properties. Nowadays, cancer is one of the main causes of mortality worldwide, therefore, ...
Mercadé Frutos, Débora (Fecha de defensa: 2018-12-13)
La tuberculosi és una infecció bacteriana causada per un micobacteri anomenat Mycobacterium tuberculosis. Actualment és la primera causa mundial de mortalitat causada per un agent infecciós fins i tot per sobre de la ...
Sallaberry Pinto, Júlia (Fecha de defensa: 2019-03-22)
Local invasion is a key cell-biological event in the metastatic cascade. In response to a changing microenvironment, cancer cells may act using two main strategies of invasion: single cell invasion and collective invasion. ...
Vargas Nadal, Guillem (Fecha de defensa: 2020-10-23)
Quatsomes are lipid-based nanovesicles developed by Nanomol group, composed of ionic surfactants and sterol derivatives. Regarding their properties, Quatsomes have shown to be highly homogenous and stable for years, important ...
Panisello Roselló, Arnau (Fecha de defensa: 2018-11-30)
Avui en dia, la única solució per a pacients que es troben en una situació de fase terminal de malaltia hepàtica o en una lesió hepàtica aguda es el transplantament. La demanda d’òrgans per a aquesta finalitat supera ...
Contreras Muñoz, Paola (Fecha de defensa: 2017-07-07)
Las lesiones del músculo esquelético son las lesiones más comunes en el ámbito deportivo (su frecuencia puede variar del 10-55%), siendo una preocupación importante en la medicina deportiva. Más del 90% de todas las lesiones ...
Arribas Hortigüela, Lorena (Fecha de defensa: 2022-06-30)
The use of imaging techniques routinely used for diagnosis and the assessment for treatment response in oncology allow us to analyze the changes in body composition that occur during treatment and how these changes impact ...
Pascual Gilabert, Marta (Fecha de defensa: 2022-11-04)
[eng] Myotonic dystrophy type 1 (DM1), one of the more complex diseases already known, is the most common and multisystemic rare neuromuscular disease among adults, without cure and limited pharmacological treatments. In ...
Vázquez Lozano, Javier (Fecha de defensa: 2019-09-13)
Three-dimensional ligand-based virtual screening methods have been used for many years in drug discovery, with a variable success depending on different factors, such as the complexity of the target system or the suitability ...