Canals Montferrer, Isaac (Date of defense: 2015-01-23)
Sanfilippo C syndrome is a lysosomal storage disorder that presents an autosomal recessive inheritance pattern and is caused by mutations in the HGSNAT gene, identified in 2006 in the chromosome 8. This ...
Calvo Lozano, Beatriz (Date of defense: 2015-10-23)
Discovering the master genes necessary to build the eye in an invertebrate model such as S. mediterranea could help us to understand numerous retinopathies and age-related degeneration of the human eye. ...
Amador Rios, Raziel (Date of defense: 2022-02-10)
Long noncoding RNAs (lncRNAs) have proven biological roles in plethora cellular contexts. Nonetheless, only a handful have been clearly characterized, leaving thousands of newly discovered lncRNAs without ...
Balcells Comas, Susana (Date of defense: 1988-01-01)
The early and late histone genes from the sea urchin Strongylocentrotus purpuratus constitute a pair of developmentally regulated genes. The early genes are expressed throughout oogenesis and early ...
Ozturk Colak, Arzu (Date of defense: 2014-12-17)
Examples of tubular organ systems like the mammalian lungs and vascular system abound in the animal kingdom. In this study we used the Drosophila melanogaster tracheal system to study tubular organ ...
Martorell Aleman, Òscar (Date of defense: 2014-03-25)
During last decades many researchers have tried to elucidate the different causes of tumour initiation and progression. For this purpose, multiple animal models have been developed to understand the ...
Mangione, Federica (Date of defense: 2016-12-13)
Within multicellular organism, mature tissues and organs reach high degrees of order in the arrangement of their constituent cells. During morphogenesis the emergence of long-range order is subjected ...
Fernández Guerra, Antonio (Date of defense: 2013-02-15)
Ammonia oxidation, the first and the rate-limiting step in nitrification, is one of the cornerstones of the cycle. Members from the bacterial and archaeal domains are key players in ammonia oxidation ...
Mineo, Alessandro (Date of defense: 2016-10-24)
The establishment of the embryonic axis in the Drosophila embryo relies on four maternal systems. Anterior and posterior axes rely on morphogens located at the poles that will generate a gradient of ...
Carrió Gaspar, Elvira (Date of defense: 2015-03-19)
Myogenesis is the differentiation process which encompasses the formation of skeletal muscle during development, regeneration and tissue homeostasis throughout life. Arising from embryonic or adult stem ...