Towards vitamin biofortification in staple cereal crops in a socio-political and food security context

Author

Farré Martinez, Gemma

Codirector

Christou, Paul

Zhu, Changfu

Date of defense

2012-07-05

Legal Deposit

L-970-2012

Pages

295 p.



Department/Institute

Universitat de Lleida. Departament de Producció Vegetal i Ciència Forestal

Abstract

Transgenic approaches hold great promise in alleviating, to a major extend such micronutrient deficiencies as exemplified by numerous reports in the literature over the past decade. However, there is a limited understanding of the regulatory mechanisms that control the accumulation of specific vitamins in plants. For this reason, I analyzed a maize population expressing combinations of the carotenogenic genes Zmpsy1, PacrtI, Gllycb, Glbch and ParacrtW in an effort to unravel as yet unknown regulatory bottlenecks.I also investigated in more detail the corn bch family. My results suggest that diverse regulatory strategies may be in operation to control the accumulation of carotenoids in endosperm tissue. I recovered multiple independent transgenic rice lines expressing Arabidopsis thaliana ρ hydroxyphenylpyruvate dioxygenase (HPPD), which catalyzes the first committed step in vitamin E biosynthesis. My results revealed bottlenecks that act as metabolic tipping points in the pathway.

Keywords

Vitamines; Biofortificació; Blat de moro; Arrós; Seguritat alimentaria; Vitaminas; Biofortifición; Maíz; Arroz; Seguridad alimentaria; Vitamin; Biofortification; Maize; Rice; Food security

Subjects

577 - Material bases of life. Biochemistry. Molecular biology. Biophysics

Knowledge Area

Bioquímica i Biología Molecular

Documents

Tgfm1de1.pdf

5.727Mb

 

Rights

L'accés als continguts d'aquesta tesi queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons: http://creativecommons.org/licenses/by-nc-nd/3.0/es/
L'accés als continguts d'aquesta tesi queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons: http://creativecommons.org/licenses/by-nc-nd/3.0/es/

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