Camilleri Robles, Carlos (Date of defense: 2022-07-22)
Long non-coding RNAs (lncRNAs) are defined as transcripts longer than 200 nucleotides that lack protein-coding potential. Although multiple examples of functional lncRNAs have been described, particularly ...
Rodriguez Fos, Elias (Date of defense: 2020-07-15)
This thesis illustrates the work I have developed as a Ph.D. student in the computational genomics group lead by Dr. David Torrents at the Barcelona Supercomputing Center. The group’s expertise in the ...
Sanchez Delgado, Marta (Date of defense: 2018-05-31)
Genomic imprinting is an epigenetic phenomenon resulting in the monoallelic expression of a subset of genes in a parent-of-origin-specific manner. In general, the promoters of these transcripts contain ...
Puerto Plasencia, Marta (Date of defense: 2022-04-01)
It has been previously shown that the Drosophila heterochromatin protein 1c (HP1c) forms a complex with the transcription factors (TF) WOC and ROW, and the extraproteasomal ubiquitin receptor dDsk2. The ...
Vizcaya Molina, Elena (Date of defense: 2018-12-19)
One of the most important questions in regenerative biology is how and when genes change expression to trigger regeneration programs. Resetting of gene expression patterns during injury responses is ...
Escoda Assens, Lídia (Date of defense: 2018-05-11)
Knowledge of the genealogical relationships among individuals of a population and their dispersal patterns are essential to many studies of endangered species, especially those with small and fragmented ...
Garrido Garcia, Alícia (Date of defense: 2022-11-10)
[eng] BACKGROUND: High-risk neuroblastoma (NB) represents a heterogeneous group of tumors, whereby patients can display response to treatment and long-term outcome or develop early progressive, ...
Mas-Ponte, David (Date of defense: 2022-11-14)
[eng] Somatic cells accumulate mutations in their genome from a set of exogenous and endogenous processes. The interplay of DNA lesions and the DNA repair mechanisms in each cell shape the genetic ...
Sellarès Rubio, Arnau (Date of defense: 2022-11-16)
[spa] El diagnóstico de enfermedades humanas originadas a causa de variantes y mutaciones en el ADN de cada persona está experimentando un cambio de paradigma, desde la aproximación genética tradicional ...
Subirana Granés, Marc (Date of defense: 2023-11-17)
[eng] Historically, cancer genomics has predominantly focused on coding regions. Current knowledge suggests that non-coding mutations are likely crucial in driving the mechanisms that regulate gene ...