Sebé Pedrós, Arnau (Date of defense: 2013-06-07)
The origin of animal multicellularity is a major evolutionary transition and a poorly understood one. In recent years, the sequencing of the genomes of several earlybranching metazoans, such as sponges ...
Lafzi, Atefeh (Date of defense: 2020-05-29)
Single-cell RNA sequencing has revolutionized the way molecular mechanisms were being studied by allowing the dissection of gene expression at single-cell resolution. The data acquired from scRNA-seq ...
Escuer Pifarré, Paula (Date of defense: 2022-12-21)
[eng] During the last decade, advances in high-throughput sequencing (HTS) technologies have increased exponentially the generation of genomic data, especially of non-model species. In this thesis, we ...
Magallón Lorenz, Miriam (Date of defense: 2023-07-07)
[eng] Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft-tissues sarcomas of the peripheral nervous system (PNS) with poor prognosis and lack of therapeutic options. Complete resection with ...
Fernández Vidal, Leyden (Date of defense: 2015-01-22)
Se ha demostrado en un número de estudios de metagenómica que la adición y la pérdida de genes específicos ha permitido a los microbiomas adaptarse a condiciones ambientales típicas de los entornos. ...
Igea de Castro, Javier (Date of defense: 2013-01-18)
Las filogenias que incorporan información procedente de distintos loci del genoma son fundamentales para resolver las relaciones evolutivas de los seres vivos, así como para determinar con precisión los ...
Sánchez Herrero, José Francisco (Date of defense: 2019-12-13)
Encontramos una gran cantidad de información genómica en bases de datos para numerosos organismos pero existe un sesgo hacia ciertos grupos taxonómicos por el interés económico, social o sanitario. Los ...
Vizueta Moraga, Joel (Date of defense: 2020-01-10)
Los artrópodos, durante su historia evolutiva, han colonizado múltiples y diversos hábitats, incluyendo eventos de terrestrialización independientes en los distintos subfilos, e implicando en algunas ...
Herrera Úbeda, Carlos (Date of defense: 2019-12-16)
In this thesis we have covered the importance of finding underlying conservation events to better understand the regulatory mechanisms of important development orchestrators like the Hox cluster. As an ...
Pitsili, Eugenia (Date of defense: 2021-11-04)
Metacaspases are a family of cysteine proteases found in lower eukaryotes and plants. They are considered to be distant relatives of caspases, present only in animals. The role of metacaspases is quite ...