Mostrando ítems 121-130 de 148
Alqahtani, Abdulateef (Fecha de defensa: 2023-10-25)
[eng] In 2001, the initial hypothesis of targeted protein degradation (TPD) was born to announce the launching of a new era of therapeutics development not by inhibiting a component of ubiquitin-proteasome ...
Galindo Camacho, Ruth Milagros (Fecha de defensa: 2023-07-07)
[spa] La inflamación, presente en diferentes enfermedades del globo ocular (escleritis, queratitis, uveítis, retinitis o neuritis óptica) y sus anexos (conjuntivitis, blefaritis o inflamación orbitaria), ...
Dumaze, Anaëlle (Fecha de defensa: 2023-11-08)
[eng] My thesis was part of a collaborative project at the interface of neuropharmacology and medicinal chemistry that aimed to better understand the neuromodulation mechanisms associated with Alzheimer’s ...
González Álamos, María (Fecha de defensa: 2023-11-21)
[eng] The vault particle, with a mass of 10 MDa and dimensions of 70 nm x 40 nm x 40 nm, is the largest ribonucleoprotein described in the eukaryotic kingdom. The vault shell is organized in two identical ...
Iannizzotto, Flavia (Fecha de defensa: 2023-12-01)
[eng] MYC dysregulation is the most common alteration in cancers, driving several cellular processes that cooperatively promote aberrant cell growth and proliferation. Among them, the induction of protein ...
Guercetti, Julian (Fecha de defensa: 2023-10-25)
[eng] The current doctoral thesis titled “Microarray Strategies for Multiplexed Immunochemical Analysis” was carried out in the context of two research projects, expecting to develop multiplexed ...
Marquès Garcia, Claudia (Fecha de defensa: 2023-12-15)
[eng] Daphniphyllum alkaloids, isolated from various species of the Daphniphyllum genus, constitute a diverse family of natural products containing over 320 distinct members and featuring more than 20 ...
Illanes Vicioso, Ramiro (Fecha de defensa: 2023-11-10)
[spa] El desarrollo de mi tesis doctoral abarca el análisis estructural y en solución de dos proteínas mitocondriales: la isoforma 1 del Factor de Transcripción A Mitocondrial (TFAM) y el dominio ...
Marzal Martí, Berta (Fecha de defensa: 2023-12-18)
[spa] El cáncer de mama es el tumor más frecuentemente diagnosticado en mujeres y entre sus diversos subtipos, en esta tesis, nos centraremos particularmente en el cáncer de mama HER2+. Esta patología ...
Murillo Villuendas, Ester (Fecha de defensa: 2023-10-20)
[eng] Polyamines are small polycationic molecules that contain amino groups and are found in all living organisms. This study is aimed at acquiring a comprehensive understanding of the diverse roles of ...