Loren Parrondo, Guillem (Date of defense: 2023-09-15)
[eng] In this doctoral thesis, the design and synthesis of bifunctional molecules that induce the degradation of a target protein in cells are described. The synthesis of molecules capable of inducing ...
Ninot Pedrosa, Martí (Date of defense: 2018-03-02)
Amyloid-beta peptide (Aβ) is strongly linked to the aetiology of Alzheimer’s disease (AD). Aβ is the main component of the amyloid plaques found in the brain of AD patients, however, Aβ is also present ...
Riefolo, Fabio (Date of defense: 2020-07-29)
Modern medical treatments are largely based on the ability of pharmacological drugs to interact with a molecular target in the human body (e.g., receptors) in order to evoke a physiological response. ...
Gómez García, Roberto (Date of defense: 2023-12-15)
[spa] La presente Tesis de carácter multidisciplinar se centra en el diseño y síntesis de nuevos derivados de C75 como potenciales agentes antitumorales e inhibidores de la ingesta para el desarrollo ...
Santiago Piera, Raul (Date of defense: 2024-02-16)
[eng] Organic chemistry is recognized for its ability to arrange a limited set of atoms in numerous ways, a quality that is crucial in molecular magnetism. This branch benefits from the adaptability of ...