Universitat de Barcelona
Now showing items 61-80 of 229
The Cytoplasmic Polyadenylation Element Binding (CPEB)-family of RNA-binding proteins is composed of four paralogs in mammals, CPEB1-4. The CPEBs control the translation of the targeted mRNAs by modulating the length of ...
The study of morphology of organisms has become a widely extended scientific discipline since the beginning of the 20th century, when the scientific community began to establish direct relationships between the anatomical ...
Increasing anthropogenic pressures and its effects on marine ecosystems urge enhanced knowledge and understanding of the current state of marine biodiversity. This baseline information is pivotal to establish the actual ...
Esta tesis se basa en diagnóstico de pacientes con deficiencia de 2 metil 3 hidroxibutiril CoA deshidrogenasa (MHBD o HSD10) y en el estudio de la fisiopatología de esta enfermedad y de su implicación en la Enfermedad de ...
El colágeno VI es una proteína de la matriz extracelular cuyos defectos conducen a una variedad de trastornos musculares en humanos caracterizados por una debilidad muscular entre otros múltiples síntomas. Tanto el colágeno ...
Breast cancer is the most frequently diagnosed cancer and remains the second leading cause of death among women in Europe and United States. In this malignancy, metastasis remains to be an incurable condition, and therefore ...
Many topics in ecology and evolution are currently being studied under the framework of eco- evolutionary dynamics that is to say integrating genetic, ecological and demographic data. Here, I have focused my investigations ...
This work aims to analytically understand the impact of two diametric opposite environments on protein structure and dynamics and compared them to the most common solvent on earth: water. The first environment is a popular ...
This thesis analyzed the dynamics of tree radial growth at different time-scales in relation to climate and drought in two tropical dry forests (TDFs) from Colombia (Tuluá) and Bolivia (INPA). The specific objectives were: ...
Classical force fields are the core of classical simulations, particularly of molecular dynamics (MD), a technique that is changing our view on the structure, flexibility and function of biological macromolecules. Originated ...
DYRK1A es un gen del cromosoma 21 humano que codifica para una proteína quinasa constitutivamente activa que fosforila a sustratos que son clave en el desarrollo del cerebro. La proteína DYRK1A regula el crecimiento del ...
The major landmark in modern genomic and biological research has been the first survey of the entire human genome. On June 2000 the staging of Bill Clinton along with Craig Venter and Francis Collins extolled how genome ...
La pancreatitis aguda és un procés inflamatori del pàncrees desencadenat per una activació inapropiada dels enzims pancreàtics. En la seva variant més severa, la malaltia progressa acompanyada d’afectacions no només a ...
Esta tesis consiste en el estudio de la regulación por microRNAs del proceso de metástasis de carcinomas ductales invasivos de mama. Hemos encontrado una expresión alterada de varios microRNAs en muestras tumorales, ...
Mitochondria are well known for their role as bioenergetic and biosynthetic organelles. Recently, they also have emerged as one of the main regulators of innate immune responses, mostly for its ability to modulate several ...
Els esfingolípids són lípids complexes derivats de l’esfingosina que a més de servir de base estructural de les membranes cel·lulars, regulen múltiples vies de senyalització, com per exemple l’autofàgia. Entre tots els ...
Breast Cancer (BC) is one of the major causes of cancer deaths in women. BC is a heterogeneous disease, and within the heterogeneity of the tumor, Tumor-Initiating Cells (TICs) have been reported as important drivers in ...
The overarching aim of my thesis was to assess the role of environmental variability and specially of perturbations in the population dynamics of social vertebrates. Our results emphasize the need to collect individual, ...
The study of intraspecific diversity is essential in ecology and evolution as they reveal fine-scale patterns and it is crucial in conservation planning. The main aim of this thesis is to study the evolutionary history of ...
El estudio se centra la filogenia, biología y ecología de la demosponja Hemimycale columella y su simbiosis con una bacteria calcificadora (calcibacteria). Posteriormente se incorporaron otras especies para entender tanto ...
