Lema Asqui, Saúl Stalin (Date of defense: 2018-06-08)
The hypersensitive response (HR) is a paradigmatic type of programmed cell death, that occurs in response to pathogen recognition at the site of attempted invasion. Notwithstanding more than a century ...
Izquierdo Bouldstridge, Andrea (Date of defense: 2018-03-13)
Seven linker histone H1 variants are present in human somatic cells with distinct prevalence across cell types. Using variant-specific antibodies to H1 and hemagglutinin-tagged recombinant H1 variants ...
Infanzón Ramos, Belén (Date of defense: 2017-09-15)
This thesis is focused in the identification and improvement of lipases for biotechnological application. The importance of lipases is increasing in several industries. However, the commercial use of ...
Planas Marqués, Marc (Date of defense: 2020-10-30)
The plant pathogen Ralstonia solanacearum is the causal agent of the devastating disease known as bacterial wilt. This disease affects more than 200 plant species in over 50 families, including economically ...
Ribó Gené, Sílvia (Date of defense: 2017-12-01)
Childhood obesity and overweight can often cause severe complications, including hypertension, dyslipidemia, insulin resistance, type 2 diabetes, and non-alcoholic fatty liver disease, amongst other ...
Burguera Hernández, Demian (Date of defense: 2017-09-22)
In the present work, we studied the evolution of alternative splicing (AS) from different perspectives. First, we performed a preliminary analysis where we identified alternative exons with tissue-specific ...
Cornet Bartolomé, David (Date of defense: 2019-07-09)
Infertility, defined by the World Health Organization (WHO) as the inability to conceive after a year of unprotected sex, is a disease that affects 1 in 9 couples of reproductive age worldwide. Most of ...
Gómez Llonin, Andrea (Date of defense: 2021-04-30)
The application of NGS techniques to the study of mature B-cell neoplasms at the research level is providing a large amount of new information, in certain cases with clinical implications, which includes ...
Benítez Álvarez, Lisandra (Date of defense: 2022-06-16)
Evolutionary Biology offers a set of methods and theories to elucidate the evolutionary processes that lead to the diversification of life. With the development of sequencing technologies, the access ...
Escuer Pifarré, Paula (Date of defense: 2022-12-21)
[eng] During the last decade, advances in high-throughput sequencing (HTS) technologies have increased exponentially the generation of genomic data, especially of non-model species. In this thesis, we ...