Pascual Alonso, Ainhoa (Date of defense: 2023-07-14)
[eng] MECP2 is a multifunctional gene involved in multiple processes such as transcription regulation, chromatin remodelling, splicing and miRNA regulation. Malfunction of MECP2 due to loss of function ...
Leria Florensa, Laia (Date of defense: 2019-10-28)
The main goal of the present thesis has been to shed light into the processes that shape the genetic diversity of organisms, focussing in the following factors: the type of reproduction, the morphological ...
Guerrero Ludueña, Richard E. (Date of defense: 2017-09-07)
Healthcare is changing, and the era of data-driven healthcare organisations is increasingly popular. Data-Driven approaches (e.g., Machine Learning, Metaheuristics, Modelling and Simulation, Data ...
Castilla-Vallmanya, Laura (Date of defense: 2021-11-04)
Neurodevelopmental disorders (NDDs) are a group of chronic diseases in which the development of the central nervous system is impaired, resulting in disability at the neuropsychiatric, motor and/or ...
Antón Galindo, Ester (Date of defense: 2021-09-17)
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social communication and interaction, as well as repetitive and restricted patterns of behaviour. Although ...
Pascual Carreras, Eudald (Date of defense: 2020-01-10)
Development requires an increment of cell growth and cell number, concomitant to a tightly control of cell differentiation. Thanks to cell communication, cells can be spatiotemporal patterned to acquire ...
Parra Acero, Helena (Date of defense: 2019-02-08)
Animal multicellular structure depends on three general mechanisms: cell adhesion, cell communication and cell differentiation. Some of these mechanisms were thought to be specific to animals. Genome ...
Herrera Úbeda, Carlos (Date of defense: 2019-12-16)
In this thesis we have covered the importance of finding underlying conservation events to better understand the regulatory mechanisms of important development orchestrators like the Hox cluster. As an ...
Olivares Castiñeira, Ivette (Date of defense: 2017-12-20)
The tracheal (respiratory) system of the Drosophila embryo is a network of interconnected epithelial tubes that supplies and exchanges the gas to maintain the homeostasis of the entire organism. Maintaining ...
Toulis, Vasileios (Date of defense: 2020-07-20)
The retina consists of several structured layers of highly specialized neurons that capture and process light stimuli enabling vision. Such a fine architecture turns retinal differentiation into an ...