Now showing items 1-20 of 181

    Dynamics of nanoparticles in 3D tumor models 

    Olea, Rodica-Alis (Date of defense: 2024-01-15)

    [eng] In the last decades, great research effort was focused towards designing nanocarriers for cancer therapy. However, nanoparticle translation from basic research to the clininc has proven to be a challenging task, with ...

    Reacciones nucleares elásticas analizadas con la fuerza de Gogny 

    López Moraña, Juan (Date of defense: 2024-01-22)

    [spa] El Modelo Óptico es una de las herramientas más esenciales para analizar experimentos de dispersión nuclear. Se basa en la hipótesis simplificada de que la interacción nucleón-nucleón individual entre el proyectil y ...

    Improving the Reliability of Conductive Atomic Force Microscopy 

    Weber, Jonas (Date of defense: 2024-04-11)

    [eng] Owing to its exceptional topographical resolution and electrical sensitivity, Conductive Atomic Force Microscopy (C AFM) has become an essential tool for nanoscale material analysis. However, achieving reproducible ...

    Development of microfluidic devices for cancer cell isolation 

    Sierra Agudelo, Jessica Nathalia (Date of defense: 2024-02-23)

    [eng] The emergence of liquid biopsies has been useful for the diagnosis of physiological conditions, inflammatory processes, and especially represents a good alternative tool for non-invasive analysis of tumor-derived ...

    Development of opto-mechanical sensors based on silicon nanopillars for biological applications 

    López Aymerich, Elena (Date of defense: 2024-01-19)

    [eng] The scope of this thesis is the advancement on the theoretical simulation and nanofabrication of photonic crystals based on a periodic array of silicon pillars. This research is intended to be part of the preliminary ...

    Coherent Flux Qubits for Quantum Annealing 

    López Núñez, David (Date of defense: 2024-04-12)

    [eng] Quantum annealing is a heuristic analog quantum algorithm that promises potential quantum speedup over classical algorithms for a huge variety of optimization problems. Current existing annealers, despite their ...

    Dynamical and Mechanical Characterisation of Bi- and Tri-dimensional Neuronal Cultures: from Health to Disease 

    Fernández López, Clara (Date of defense: 2024-01-12)

    [eng] In this PhD thesis, we leverage the well established foundations of complex systems physics and integrate insights from medicine and materials engineering to advance our understanding of neuroscience. Our primary ...

    Decadal climate prediction and predictability for climate services 

    Delgado Torres, Carlos (Date of defense: 2024-02-14)

    [eng] Climate variations at annual to decadal time scales affect many regions around the globe, causing direct impacts on the economy, ecosystems and society. Knowing these variations in advance allows for implementing ...

    Active turbulence and active shell models for microswimmer suspensions 

    Gascó Patiño, Toni (Date of defense: 2024-02-05)

    [eng] This doctoral thesis deals with the study of the collective behavior of active particles using computacional simulations of semi-dilute solutions of microswimmers. Results are obtained for the polar order parameter, ...

    3D in vitro models for neural progenitor cell differentiation and network formation 

    Pereira, Inês Sousa (Date of defense: 2023-10-17)

    [eng] Conventional 2D in vitro and animal models have been found inadequate to fully uncover the intricate mechanisms happening in the brain and its diseases. Engineering-based models emerge as promising alternatives to ...

    Domain walls, primordial black holes and inflation 

    Sanglás Martín, Albert (Date of defense: 2023-10-10)

    [eng] This thesis investigates primordial black holes and their observational consequences. In the first part, we examine the behavior of domain walls produced during inflation, and their subsequent collapse, leading to ...

    Towards a better characterization of submicron aerosol in the Mediterranean basin 

    Via González, Marta (Date of defense: 2023-09-19)

    [eng] Atmospheric aerosol is an ensemble of atmospheric pollutants with a severe impact on human health and Earth climate. Particulate Matter (PM) effects vary depending on the composition and size. However, current air ...

    Engineering in vitro models of the intestinal mucosa to study the role of the stroma on the epithelium 

    Abad i Lázaro, Aina (Date of defense: 2023-07-20)

    [eng] The standard in vitro model of the small intestine in the field of drug development still consists in a monolayer of cancer-derived cells seeded on a hard substrate. Despite the huge advances that this model has ...

    Nanoscale Multimodal Characterization of Operating Electrolyte-Gated Transistors 

    Tanwar, Shubham (Date of defense: 2023-07-28)

    [eng] Electrolyte-gated transistors (EGTs) have emerged as key platforms for transducing and amplifying biological and biochemical signals, making them an integral part of diverse biosensing and bioelectronic applications ...

    Métodos avanzados de microscopía de fuerzas electrostáticas para el estudio de muestras biológicas 

    Millán Solsona, Rubén (Date of defense: 2023-07-10)

    [spa] Las propiedades dieléctricas de las células han sido objeto de una intensa investigación a lo largo de los años debido a su relevancia en muchos problemas biológicos fundamentales. Destacamos la importancia de la ...

    Thermodynamics and Kinetics of Nucleic Acids Folding 

    Rissone, Paolo (Date of defense: 2023-04-20)

    [eng] This doctoral work investigates nucleic acids' thermodynamic and kinetic properties. The main objective is the characterization of the energetics and the folding mechanisms driving the hybridization of DNA and RNA ...

    Biomechanics of the progression of colorectal carcinomas 

    Fornabaio, Giulia (Date of defense: 2023-04-14)

    [eng] Living tissues are active materials with the ability to undergo drastic shape and dimension transitions. If properly controlled, these morphological changes allow various physiological phenomena such as embryonic ...

    Advanced Characterization of Interfaces of the Chalcogenide-Based Absorbers for the Thin Film Photovoltaic Technologies 

    Fonoll i Rubio, Robert (Date of defense: 2023-03-06)

    [eng] The thesis Advanced Characterization of Interfaces of the Chalcogenide-Based Absorbers for the Thin Film Photovoltaic Technologies is based on six articles that are published in high impact factor peer-reviewed ...

    Calculations of water free energy in bulk and large biological systems 

    Coronas Serna, Luis Enrique (Date of defense: 2023-03-28)

    [eng] This thesis develops, validates, and explores applications of the Franzese-Stanley (FS) coarse-grained model for bulk water, ultimately intended to represent the solvent in large-scale simulations of biological ...

    Testing the Standard Model with radiative beauty and rare strange decays at LHCb 

    Gironella Gironell, Pere (Date of defense: 2023-03-28)

    [eng] This thesis focuses in the analysis of radative b-decays and rare strange decays, using data recorded by the LHCb, at the LHC during the Run 2 period. Two analyses are presented in the thesis, both flavour changing ...