Puig Saus, Cristina (Date of defense: 2013-07-15)
La viroteràpia amb adenovirus oncolítics es basa en la lisi selectiva de la cèl•lula tumoral a través de la replicació viral. Les principals limitacions d’aquesta teràpia són: la limitada arribada del ...
Hosseini, Seyed Ali (Date of defense: 2015-05-08)
A complete understanding of complex formation between proteins and ligands, a crucial matter for pharmacology and, more in general, in biomedicine, requires a detailed knowledge of their static and ...
Elias Miró, Maria (Date of defense: 2014-01-24)
La presente tesis se enmarca dentro del estudio de la lesión por isquemia-reperfusión (I/R), y sus efectos sobre la regeneración, en hígados esteatósicos y no esteatósicos. Uno de los principales riesgos ...
Peric, Brezana (Date of defense: 2014-12-17)
Ionic liquids (ILs) are a fairly new and very promising group of compounds. They are often considered as environmentally benign substitutes for traditional volatile organic solvents due to their attractive ...
Sima Teruel, Núria (Date of defense: 2016-06-30)
La cromatina és una estructura nucleoproteica, dinàmica i jeràrquicament organitzada dins del nucli cel•Iular. La seva estructura, organització i funció està controlada al llarg del cicle cel.lular, ...
de la Puente Robles, Beatriz (Date of defense: 2015-12-18)
The present Doctoral Thesis focuses on the study of the sigma-1 receptor (σ1R) in the field of pain. This research has been a part of the preclinical σ1R project focusing on drug discovery of σ1R ligands ...
Suñé i Negre, Josep M. (Josep Maria) (Date of defense: 1987-01-01)
Se realiza un amplio estudio experimental con el fin de mejorar el ensayo de control de calidad de la fácil ruptura de las ampollas de uso farmacéutico que presentan esta característica, aplicando una ...
Püschel, Franziska (Date of defense: 2019-10-31)
Metabolic alterations in cancer cells are primarily caused by oncogenic mutations and cancer cells are more dependent on glucose compared to non-transformed tissue. Targeting the cancer metabolism opens ...
Gil Sepúlveda, Victor Alejandro (Date of defense: 2016-06-09)
The pharmaceutical industry is actively looking for new ways of boosting the efficiency and effectiveness of their R&D programmes. The extensive use of computational modeling tools in the drug discovery ...
Tintoré Gazulla, Maria (Date of defense: 2015-07-01)
The O6-alkylguanine DNA alkyltransferase (hAGT or MGMT) is a DNA repair protein in charge of removing alkyl adducts from the O6 position of guanines, blocking their cytotoxic effects and playing an ...