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PET in preclinical AD: image harmonization, characterization of the centiloid metric of Aβ load and associations with tau fluid biomarkers 

Shekari, Mahnaz (Date of defense: 2024-04-03)

This thesis explores technical factors influencing brain PET quantification, developing brain PET harmonization framework, assessing Centiloid robustness as a clinical biomarker, and evaluating the associations between ...

Decoding the epitranscriptomic complexity through computational methods based on long-read sequencing 

Delgado Tejedor, Anna (Date of defense: 2024-03-21)

RNA modifications, collectively known as the ‘epitranscriptome’, play a major role in multiple biological processes, including splicing regulation, gene expression regulation and antibiotic resistance. Unfortunately, ...

Development of a low input chromatin profiling technique to examine the role of PRC2 proteins in development and leukaemia 

Sondermann, Nathalie Allegra Faye (Date of defense: 2024-03-21)

Polycomb repressive complexes (PRC1/2) are key chromatin regulators in development. Their deregulation is implicated in various cancers including leukaemia. Meanwhile, MLL-rearrangements by chromosomal translocations and ...

Influencias del entorno alimentario de los centros educativos sobre el peso de los escolares 

Londoño Cañola, Catalina (Date of defense: 2024-03-18)

Esta tesis tiene como objetivos evaluar el entorno alimentario alrededor de las escuelas de Barcelona en términos de proximidad y disponibilidad de establecimientos alimentarios y su relación con el nivel socioeconómico ...

Trata de seres humanos como criminalidad económica: análisis sustantivo y procesal penal 

Torres Ferrer, Clàudia (Date of defense: 2024-03-01)

En les últimes dècades el fenomen del tràfic d'éssers humans (TEH) ha estat objecte de nombrosos estudis, debats i iniciatives legislatives. Recentment, no obstant això, el vessant econòmic del TEH ha despertat un interès ...