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Now showing items 29738-29757 of 41723
New clinical trial designs applied to the study of orphan and rare diseases: feasibility of methodological guidance to clinical development of new treatments from a regulatory perspective
Las incertidumbres reguladoras asociadas a las autorizaciones de comercialización de medicamentos huérfanos con frecuencia se relacionan con la realización de desarrollos clínicos poco convencionales, obstaculizados por ...
New clinico-pathological findings and prognostic factors of canine leishmaniasis in endemic and nonendemic areas
Canine Leishmaniasis (CanL) is due to Leishmania infantum (syn. Leishmania chagasi) and is endemic in Mediterranean countries, Portugal, Latin America and Southern Asia. In the last few decades, imported and even autochthonous ...
New colonial rescue. Appropriating a feminist discourse in the war on terror
Esta tesis es un análisis crítico del discurso de la Guerra contra el Terrorismo (GCT) y la representación de las mujeres del Oriente Medio (OM). Mi tesis se resume en que este discurso ha esencializado las mujeres del OM ...
New Computational Methods for Automated Large-Scale Archaeological Site Detection
Aquesta tesi doctoral presenta una sèrie d'enfocaments, fluxos de treball i models innovadors en el camp de l'arqueologia computacional per a la detecció automatitzada a gran escala de jaciments arqueològics. S'introdueixen ...
New computational methods for structural modeling protein-protein and protein-nucleic acid interactions
[eng] The study of the 3D structural details of protein-protein and protein-DNA interactions is essential to understand biomolecular functions at the molecular level. Given the difficulty of the structural determination ...
New concepts for electrical detection of biomolecules
Aquest treball discuteix difrerents aspects relacionats amb el disseny de sensors i sistemes de biodetecció. Descriu la fabricació i caracterització de transductors electrics particulars, així com el desenvolupament de ...
New contributions to algorithms and tools for the analysis of photometric and spectroscopic time-series in exoplanet searches
The current trend in exoplanet research focuses on the detection and characterisation of Earth-sized planets, and the study of their potential subtle and tenuous atmospheres. The aim of this thesis is the development of ...
New contributions to the ecology of gelatinous zooplankton in the Western Mediterranean: abundance, distribution and diversity
[eng] Gelatinous zooplankton has been studied in the Western Mediterranean for a long time, however, its spatial structure has been mainly addressed in coastal areas, during spring and summer periods. Hence, information ...
New contributions to the preparation of compounds derived from L-cysteine with biological activity
Una gran varietat de productes naturals i fàrmacs que inclouen sofre en les seves estructures presenten diverses activitats biològiques i aplicacions. Un exemple és la L-cisteïna, un aminoàcid essencial necessari en processos ...
New data integration methods for drug re-purposing by mining heterogeneous omics data
(English) High-throughput omics technologies produce large-scale heterogeneous data that provide complementary views of the underlying complexity of the studied organism. To exploit these new data to answer biomedical ...
New design considerations for seismic isolated buildings in Colombia
An important percentage of Colombian population is located in medium-to-high seismicity zones (NSR-10, 2010). Therefore, it is important to protect the buildings, principally the highly crowded ones, and those that are ...
New design proposal to mimic the joint structure between bone and hyaline cartilage
En el disseny de dispositius mèdics existeixen diversos casos en els quals és necessària la utilització de superfícies bioactives per aconseguir la integració òptima d’un implant amb el teixit que l’envolta. L’enginyeria ...
New determinants of bilateral trade: An empirical analysis for developed and developing countries
In this dissertation, the pattern and direction of international trade flows will be analysed by taking into consideration different levels of development across countries in the world. A better understanding of the factors ...
New developments in calcium phosphate bone cements: approaching spinal applications
La presente tesis doctoral (i.e., “New developments in calcium phosphate bone cements: approaching spinal applications”) aporta nuevos conocimientos en el campo de los cementos óseos de fosfato de calcio (CPBCs) en relación ...
New developments in the measurement of market connectedness
Esta tesis consiste en tres partes. El objetivo de este estudio es cuantificar de forma dinámica la conexión de mercado mediante el uso de rentabilidad y volatilidad desbordamientos. La primera parte es un estudio metodológico ...
New developments on preparation of cooled and bunched radioactive ion beams at ISOL-Facilities: the ISCOOL project and the rotating wall cooling
Last years have become very productive for the research, construction and development of new facilities devoted to the production of beams with exotic radioisotopes (Radioactive Ion Beams, RIB). These beams are later used ...
New developments to refine target, suspect and non-target screening strategies for comprehensive monitoring of the aquatic environment
The amount of organic micropollutants (OMP) currently being released to the aquatic environment is incommensurable. Thus, different analytical strategies were developed over the recent years to monitor the occurrence of ...
New Directions in Aminocatalysis: Vinylogy and Photochemistry
Durant els darrers 15 anys, la organocatàlisi ha atret l'atenció de nombrosos grups de recerca, per aquest motiu, trobar nous conceptes en aquest camp no resulta gens senzill actualment. En aquesta tesi hem aconseguit ...
New Electrochemical Sensors for Decentralized Analysis
Nous sensors electroquímics per a analisis decentralitzats és una tesis que emmarca diferents aspectes del desenvolupament de sensors potenciomètrics, des de la seva fabricació, el diseny adequat, i finalment, la seva ...
