Characterization of mechanisms underlying neuronal survival and plasticity in Huntington's disease 

Anglada Huguet, Marta (Date of defense: 2013-07-22)

Huntington’s disease is a progressive neurodegenerative disorder caused by the expansion of a CAG tract in the exon-1 of the huntingtin gene. Mutant huntingtin induces a large amount of toxic effects that trigger cell ...

Characterization of microcellular plastics for weight reduction in automotive interior parts 

Gómez Monterde, Javier (Date of defense: 2017-02-17)

The present PhD thesis is framed within the Industrial Doctorate Plan promoted by the Generalitat de Catalunya and has been developed in cooperation between the Universitat Politècnica de Catalunya-BarcelonaTech, the Centre ...

Characterization of mixing and spreading in heterogeneous media 

Zavala Sánchez, Gabriela Vanessa (Date of defense: 2008-07-02)

Characterization of molecular mechanisms of acquired resistance to Trastuzumab in gastric cancer 

Sampera Borràs, Aïda (Date of defense: 2018-11-20)

The HER2 receptor is overexpressed in 7-34% of gastric cancer (GC) tumors, being a potential therapeutic target. Trastuzumab, an anti-HER2 monoclonal antibody, in combination with platinum therapy was approved in 2010 as ...

Characterization of morphogenes and new transcription factors involved in the development of striatal medium spiny neurons 

Pardo Muñoz, Mònica (Date of defense: 2015-11-12)

The striatum is one of the brain structures that controls body movement. In humans the striatum consists of two nuclei, the caudate and putamen which are separated by the internal capsule, while in mice it is a single ...

Characterization of mRNA expression and localization in synaptic plasticity 

Mendoza Blanco, Mónica (Date of defense: 2023-11-24)

[eng] Neurons are highly polarized cells that require protein synthesis in distal dendrites to fulfil local protein requirements on short timescales. The regulation of this process relies in two major sub processes: the ...

Characterization of nanofibers produced by electrospinning for biomedical applications 

Akdemir, Reyda (Date of defense: 2023-11-16)

L'electrospinning o electrofilat és una tècnica versàtil i innovadora que s'utilitza per produir fibres ultrafines amb un diàmetre mitjà en un rang que va des de nanòmetres a micròmetres. Es basa en l'aplicació d'un camp ...

Characterization of nanomechanical resonators based on silicon nanowires 

Sansa Perna, Marc (Date of defense: 2013-07-23)

Els sensors de massa nanomecànics han atret un gran interès darrerament per la seva alta sensibilitat, que ve donada per les petites dimensions del ressonador que actua com a element sensor. Aquesta tesi tracta sobre la ...

Characterization of nanostructured materials for thermal conduction and heat transfer control 

El Sachat, Alexandros (Date of defense: 2017-06-27)

L'objectiu principal d'aquesta tesi és l'estudi de les propietats tèrmiques de materials nanoestructurats com un mitjà per controlar el transport de calor. Per a aquest propòsit s’han portat a terme mesures tèrmiques amb ...

Characterization of natural Killer cell response to human cytomegalovirus infected dentrilic cells 

Magri, Giuliana (Date of defense: 2011-03-31)

S'ha establert un sistema experimental autòleg per a poder estudiar la resposta de les cèl.lules Natural Killer (NK) contra les cèl.lules dendrítiques derivades de monòcits (moDC), infectades pel Cytomegalovirus humà (HCMV). ...

Characterization of natural populations of Arabidopsis thaliana differing in tolerance to carbonate soil 

Terés Gelabert, Joana (Date of defense: 2017-10-05)

S’han investigat les poblacions naturals d’Arabidopsis thaliana de Catalunya per identificar mecanismes d’adaptació local als sòls carbonatats. Després de caracteritzar les propietats químiques dels sòls natius, petits ...

Characterization of new mutations in transferrin, DMT1 and SEC23B causing rare iron metabolism-related diseases; and the discovery of RACGAP1 as the gene responsible for autosomal recessive congenital dyserythropoietic anaemia type III 

Romero Cortadellas, Lídia (Date of defense: 2023-09-22)

Iron is a biometal involved in many physiological processes that are essential for life. Iron metabolism is a complex and tightly regulated process both at the systemic and cellular level. Proper iron homeostasis relies ...

Characterization of non-Saccharomyces wine yeasts during desiccation stress imposition 

Roca Domènech, Gemma (Date of defense: 2018-10-17)

L’objectiu principal d’aquest estudi és la caracterització fisiològica de llevats vínics no-Saccharomyces sota l’estrès de deshidratació. Actualment, els Llevats Vínics Secs Actius (LVSA) són extensament usat per la producció ...

Characterization of novel actionable molecular subgroups in Hepatocellular Carcinoma: Immune class and IGF2-driven tumors 

Martínez Quetglas, Iris (Date of defense: 2018-01-09)

Insulin-like growth factor (IGF) signaling is frequently altered in HCC, including activation of IGF1R, IGF2 overexpression, IGFBP3 downregulation and IGF2R allelic losses1,2. A previous study from our group identified ...

Characterization of novel Hhex partners: SOX13 and c-Myc. New mechanism for the regulation of Wnt/TCF and c-Myc pathways 

Marfil Vives, Vanessa (Date of defense: 2010-07-22)

Hhex transcription factor is expressed in multiple endoderm-derived tissues, like the liver, where it is essential for proper development. The pleiotropic effect of Hhex in the embryo and its dual role as a transcriptional ...

Characterization of Oenococcus oeni and other lactic acid bacteria from the vine-wine ecosystem in Priorat 

Franquès Montserrat, Judith (Date of defense: 2018-09-28)

Oenococcus oeni, l’espècie de bacteris làctics (BL) principal responsable de la fermentació malolàctica (FML), s'ha aïllat repetidament dels vins, però quasi mai des del raïm. En aquesta tesi, la biodiversitat de BL de ...

Characterization of plant cellular responses upon pathogen-induced RNA silencing suppression 

Villar Martin, Luis Manuel (Date of defense: 2022-01-21)

que regular la producción de distintos efectores para explotar completamente al huésped en su propio beneficio. El silenciamiento génico mediado por ARN es un mecanismo de defensa antiviral y, como tal, está sometido a ...

Characterization of pneumonia among children under five years of age hospitalized in Thimphu, Bhutan 

Jullien, Sophie (Date of defense: 2021-03-23)

[eng] The general objective of this thesis was to describe the epidemiology, aetiology, clinical presentation, and radiological findings of pneumonia among Bhutanese children to better characterize childhood pneumonia in ...

Characterization of polymers and Microencapsulated Phase Change Materials used for Thermal Energy Storage in buildings 

Giró Paloma, Jessica (Date of defense: 2015-11-27)

The use of renewable heat decreases the consumption of fossil resources, although its usage is intermittent and usually does not match the demand. A proper thermal energy storage system design can eliminate this problem ...

Characterization of resistant Cucumis germplasm to manage root-knot nematodes Meloidogyne spp. 

Expósito Creo, Alejandro (Date of defense: 2021-02-05)

Plant resistance through grafting susceptible scions onto resistant rootstocks is an effective measure to supress root-knot nematode (RKN) populations and to reduce crop yield losses. However, the reiterative use of specific ...