Mostrando ítems 1-10 de 57
Martínez Campanario, María del Carmen (Fecha de defensa: 2021-05-27)
Macrophages polarization from an inflammatory to a tolerogenic state occurs in both physiological and pathological, and this reprogramming is key in the development of several diseases as different as ...
Rodríguez-Vida Rodríguez, Alejo (Fecha de defensa: 2017-10-23)
Prostate cancer is the second most frequently diagnosed cancer worldwide and the fifth leading cause of cancer death in men. Despite, the above mentioned incidence and mortality, the existence of a small ...
Roura Fornells, Esther (Fecha de defensa: 2018-10-22)
The objective of this thesis is to estimate prospectively the association between environmental cofactors and the risk of developing cervical cancer and pre-cancer, including tobacco smoking, hormonal ...
Vegliante, Maria Carmela (Fecha de defensa: 2013-09-26)
Mantle cell lymphoma (MCL) is an aggressive subtype of non-Hodgkin lymphomas associated with poor prognosis and frequent relapses. Recently, the neuronal transcription factor SOX11 has been identified ...
Recalde-Percaz, Leire (Fecha de defensa: 2021-06-30)
Metastases are considered the last stage of tumour progression and the main cause of death associated to solid tumours. There are no effective treatments for metastasis which remain non- curable with ...
Bassani, Nicklas (Fecha de defensa: 2017-12-15)
Antiangiogenic drugs are used clinically for treatment of different types of cancers and in the case of renal cell carcinoma (RCC) are now standard first-line treatments (Rini, 2009). Nevertheless, these ...
Vidal Crespo, Anna (Fecha de defensa: 2017-04-28)
In this thesis we have focused on two novel therapeutic strategies that target the crosstalk between the tumor cells and the microenvironment. Chronic lymphocytic leukemia (CLL) remains an incurable ...
Llorente Lope, Alicia (Fecha de defensa: 2021-03-23)
Metastatic breast cancer (BCa) is the leading cause of death in BCa patients. Current therapies for BCa aim at cell proliferation and, therefore, latent disseminated cells are able to escape treatment. ...
Benítez, Sandra (Fecha de defensa: 2021-01-13)
Receptor activator of nuclear factor kappa-β ligand (RANKL) and its receptor RANK are key mediators of bone resorption1,2. RANKL, its receptor RANK and its natural decoy receptor OPG, which is a competitive ...
Noguera-Castells, Aleix (Fecha de defensa: 2022-01-31)
Modern oncology conceives solid tumours as organs by themselves, meaning that not only should the behaviour of cancer cells to be considered and evaluated therapeutically, but also the so-called tumour ...