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Showing 10 out of a total of 268 results for community: Universitat de Barcelona. (1.999 seconds)

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Involvement of the Microtubule-Regulated RhoGEF GEF-H1 in the G12 family signaling pathways

Garrido Antequera, Georgina (Date of defense: 16-09-2014)
Heterotrimeric G proteins are masters regulators of cell homeostasis. They coordinate the signaling between G protein coupled receptors (GPCRs) and their intracellular effectors. Heterotrimeric G proteins are composed of ...
Environmental cues controlling the pathogenicity of "Ralstonia solanacearum" on plants / Señales ambientales que determinan la patogenicidad de "Ralstonia solanacearum" en plantas

Oliveira Monteiro, Freddy Miguel de (Date of defense: 28-06-2013)
Ralstonia solanacearum is a soil-borne beta-proteobacterium that causes wilting disease on a wide range of plants with economic importance like tomato, potato, pepper, eggplant and banana. Each year, bacterial wilt pose ...
Estudio de la longitud telomérica e identificación de nuevos genes causales en el cáncer colorrectal hereditario no polipósico

Seguí Gracia, Núria (Date of defense: 17-07-2014)
Aunque se estima la proporción de casos de cáncer colorrectal (CCR) atribuibles a factores genéticos entre el 20 y 35%, gran parte de la herencia genética al CCR queda por descubrir. Dentro de ese conglomerado de casos de ...
Genomic analysis of epithelial fusion and wound healing morphogenetic processes in Drosophila / Análisis genómico de los procesos morfogenéticos de fusión de epitelios y cicatrización en Drosophila

Álvarez Fernández, Carmen (Date of defense: 26-04-2013)
This thesis is based on a genomic study of the epithelial fusion and wound healing processes using Drosophila melanogaster as a model system. The aimed of the work is to study the genomic differences between cells actively ...
The contribution of LMO4 to neural development: generatin neuronal subtypes in the dorsal spinal cord and controlling EMT in neural crest cells and Neuroblastoma = La contribución de LMO4 al desarrollo neural: la generación de subtipos neuronales de la médula dorsal espinal y el control de la EMT en las células de la cresta neural y de Neuroblastoma

Ferronha, Tiago Guimaràes (Date of defense: 16-07-2013)
The formation of the central nervous system (CNS) requires the generation of a remarkable diversity of neurons, which must be produced in adequate amounts in the location and timing during development. Studies on the ...
The role of the zebrafish tbx5 paralogues during eye, pectoral fin and heart development.

Pi Roig, Aina (Date of defense: 06-04-2018)
Tbx5 is a transcription factor expressed in the developing eyes, heart and upper limbs. Mutations in human TBX5 cause Holt-Oram syndrome (HOS), a condition characterised by heart and upper limb malformations. In zebrafish, ...
The Identification and the Functional Validation of Eye Development and Regeneration Genes in Schmidtea Mediterranea

Calvo Lozano, Beatriz (Date of defense: 23-10-2015)
Discovering the master genes necessary to build the eye in an invertebrate model such as S. mediterranea could help us to understand numerous retinopathies and age-related degeneration of the human eye. The aim of this ...
Elucidating the molecular basis of Lynch-Like syndrome

Vargas Parra, Gardenía María (Date of defense: 19-02-2016)
BACKGROUND: MMR deficiency is a hallmark of tumors from Lynch syndrome LS) patients, who harbor germline mutations in MMR genes. No germline alterations are detected in a significant proportion of suspected LS now known ...
Evolutionary recruitment and assembly of embryonic alternative splicing programs: insights form the Deuterostomia lineage

Burguera Hernández, Demian (Date of defense: 22-09-2017)
In the present work, we studied the evolution of alternative splicing (AS) from different perspectives. First, we performed a preliminary analysis where we identified alternative exons with tissue-specific regulation in ...
Mètodes estadístics per al refinament del diagnòstic dels síndromes limfoproliferatius de cèl·lula B

Clot Razquin, Guillem (Date of defense: 12-09-2017)
Els síndromes limfoproliferatius crònics de cèl·lula B (B-CLPD) engloben diverses entitats heterogènies de tumors hematològics. Aproximadament un 15% dels casos no es poden classificar correctament en cap entitat mitjançant ...