Universitat de Barcelona
Now showing items 57-76 of 101
Pharmaceuticals which are used worldwide are designed to facilitate the life for the human society and have an important role in treatment and prevention of disease for both humans and animals. They are ubiquitous in the ...
In the present thesis we have investigated the development of new methodologies for the selective and straightforward chemical modification of Trp amino acid either alone or in peptides. In the first chapter, we have ...
1. The Force Field Accuracy Problem. The utility and applicability of MD simulations to model biomolecular systems goes only as far as its ability to sufficiently sample the conformational space and the correct description ...
Exposure to nanoparticles has been associated with adverse effects on human health. When the exposure route is inhalation, nanoparticles can cause pulmonary inflammation which may be more severe than from fine particles, ...
L’objecte primordial del present treball ha estat l’estudi teòric i pràctic d’un solvent, l’alcohol terc-butílic, que tot i essent un dels solvents més semblants a l’aigua, presenta respecte a ella notables diferències. ...
[spa] Los estudios sobre exposición a nanopartículas (NP) en aerosoles atmosféricos son cada vez más importantes para comprender sus efectos en la salud humana y el medio ambiente, ya que las NP pueden penetrar profundamente ...
[eng] Somatic cells accumulate mutations in their genome from a set of exogenous and endogenous processes. The interplay of DNA lesions and the DNA repair mechanisms in each cell shape the genetic mosaicism that composes ...
La xantinoxidasa (xantina: oxígeno-oxidorreductasa) fue descubierta por HORBACZEWSKI y SPITZER al observar que la hipoxantina y la xantina, en presencia de varios preparados tisulares, daban lugar a la aparición de ácido ...
To direct post-transcriptionally gene silencing, RNAi machinery exploits the formation of base pairs between the loaded guide strand and the complementary mRNA. The Ago2 protein is the “slicer” effector of the RISC and ...
[eng] Global warming and climate change, mostly due to the increasing concentration of greenhouse gases in the atmosphere, are producing devastating effects. Among the different greenhouse gases, CO2 is one of the major ...
[eng] MXene materials, the low-dimensional counterpart of transition metal carbides and nitrides present suitable properties as catalysts in heterogeneous catalysis given the similar properties with transition metal carbides ...
Over the recent decades, several studies revealed the precarious climate situation which is threatening all Life forms on earth, including mankind, even if sometimes we tend to ignore the actual fragility of our situation. ...
[eng] Historically, cancer genomics has predominantly focused on coding regions. Current knowledge suggests that non-coding mutations are likely crucial in driving the mechanisms that regulate gene activity, potentially ...
The Immune System (IS) is a complex collection of tissues, organs, cells and molecules to defense the body against threatens. IS is organized into two lines of defense: innate immunity which acts in a non-specific manner ...
Cysteine (Cys) is a unique amino acid due to its ability to form reversible covalent disulfide bonds. These bonds cause conformational constraints which make peptides or proteins more rigid and stable. In addition, the ...
In the present thesis, analytical methods based on gas chromatography coupled with mass spectrometry, both single (GC-MS) or tandem (GC-MS/MS), have been developed and optimized for the detection and quantification of ...
Dust has been used as a surrogate of indoor organic contamination for several decades. Their concerns for human health include from sensitization effects such as allergies to toxic effects derived from those organic ...
Cyanobacteria are prokaryotes and components of regular periphyton formation. Overall, there are around 2000 cyanobacterial species that live in various environments. Some cyanobacterial species are known to form blooms, ...
[eng] Remote high mountains allow the study of the environmental fate of legacy and emerging anthropogenic chemicals that form a worldwide diffuse background layer of pollution. Semi- volatile compounds like polychlorinated ...
The assessment of pesticide occurrence in different environmental compartments has become a matter of outstanding importance since its effects on exposed organisms may be considered a warning on the potential risk these ...
