Now showing items 61-80 of 101

    L'alcohol terc-butílic com a solvent d'interés analític: equilibris protolítics i les seves aplicacions 

    Rosés Pascual, Martí (Date of defense: 1986-05-23)

    L’objecte primordial del present treball ha estat l’estudi teòric i pràctic d’un solvent, l’alcohol terc-butílic, que tot i essent un dels solvents més semblants a l’aigua, presenta respecte a ella notables diferències. ...

    Liberación de partículas atmosféricas en escenarios industriales reales y su impacto en la exposición humana y ambiental. Casos de estudio: actividades portuarias y reciclaje de residuos electrónicos 

    López Olivé, Maria (Date of defense: 2023-09-15)

    [spa] Los estudios sobre exposición a nanopartículas (NP) en aerosoles atmosféricos son cada vez más importantes para comprender sus efectos en la salud humana y el medio ambiente, ya que las NP pueden penetrar profundamente ...

    Localized hypermutation and hypomutation in the genomes of human somatic cells 

    Mas-Ponte, David (Date of defense: 2022-11-14)

    [eng] Somatic cells accumulate mutations in their genome from a set of exogenous and endogenous processes. The interplay of DNA lesions and the DNA repair mechanisms in each cell shape the genetic mosaicism that composes ...

    Mecanismo cinético de la xantinoxidasa de hígado de buey y de la xantindeshidrogenasa de hígado de pollo 

    Canela Campos, Enric I. (Date of defense: 1976-12-16)

    La xantinoxidasa (xantina: oxígeno-oxidorreductasa) fue descubierta por HORBACZEWSKI y SPITZER al observar que la hipoxantina y la xantina, en presencia de varios preparados tisulares, daban lugar a la aparición de ácido ...

    Modulation of the RNAi pathway by chemically modified siRNA molecules 

    Alagia, Adele (Date of defense: 2015-12-11)

    To direct post-transcriptionally gene silencing, RNAi machinery exploits the formation of base pairs between the loaded guide strand and the complementary mRNA. The Ago2 protein is the “slicer” effector of the RISC and ...

    Multiscale modelling of CO2 hydrogenation reactions on Ni-based catalysts 

    Lozano Reis, Pablo (Date of defense: 2023-11-10)

    [eng] Global warming and climate change, mostly due to the increasing concentration of greenhouse gases in the atmosphere, are producing devastating effects. Among the different greenhouse gases, CO2 is one of the major ...

    MXene Materials for CO(2) Capture and Transformation 

    Jurado Mañas, Anabel (Date of defense: 2023-06-21)

    [eng] MXene materials, the low-dimensional counterpart of transition metal carbides and nitrides present suitable properties as catalysts in heterogeneous catalysis given the similar properties with transition metal carbides ...

    Nanostructured transition metal carbides as potential catalysts for greenhouse gases conversion 

    Figueras Valls, Marc (Date of defense: 2021-12-14)

    Over the recent decades, several studies revealed the precarious climate situation which is threatening all Life forms on earth, including mankind, even if sometimes we tend to ignore the actual fragility of our situation. ...

    Non-coding genome functions in cancer 

    Subirana Granés, Marc (Date of defense: 2023-11-17)

    [eng] Historically, cancer genomics has predominantly focused on coding regions. Current knowledge suggests that non-coding mutations are likely crucial in driving the mechanisms that regulate gene activity, potentially ...

    Non-glycosidic analogues of alpha-galactosylceramide: Design, synthesis and biological activity 

    Borràs Tudurí, Roser (Date of defense: 2018-07-06)

    The Immune System (IS) is a complex collection of tissues, organs, cells and molecules to defense the body against threatens. IS is organized into two lines of defense: innate immunity which acts in a non-specific manner ...

    Novel Disulfide Formation Strategies in Peptide Synthesis 

    Postma, Tobias Maria (Date of defense: 2014-03-21)

    Cysteine (Cys) is a unique amino acid due to its ability to form reversible covalent disulfide bonds. These bonds cause conformational constraints which make peptides or proteins more rigid and stable. In addition, the ...

    Occurrence and distribution of organochlorinated pesticides and flame retardants in Spain and China 

    Zapata Corella, Pablo (Date of defense: 2022-09-19)

    In the present thesis, analytical methods based on gas chromatography coupled with mass spectrometry, both single (GC-MS) or tandem (GC-MS/MS), have been developed and optimized for the detection and quantification of ...

    Organic pollutants in indoor dust: method development, site-specific monitoring and human exposure 

    Velázquez Gómez, Miquel (Date of defense: 2019-10-21)

    Dust has been used as a surrogate of indoor organic contamination for several decades. Their concerns for human health include from sensitization effects such as allergies to toxic effects derived from those organic ...

    Origin and release of cyanotoxins in surface water reservoirs 

    Filatova, Daria (Date of defense: 2021-07-20)

    Cyanobacteria are prokaryotes and components of regular periphyton formation. Overall, there are around 2000 cyanobacterial species that live in various environments. Some cyanobacterial species are known to form blooms, ...

    Passive air and water sampling in high-altitude lakes: occurrence and distribution of legacy and emerging organic pollutants 

    Martínez Prats, Raimon (Date of defense: 2022-11-17)

    [eng] Remote high mountains allow the study of the environmental fate of legacy and emerging anthropogenic chemicals that form a worldwide diffuse background layer of pollution. Semi- volatile compounds like polychlorinated ...

    Pesticides in the environment: analysis, occurrence, impact and recommendations for their attenuation 

    Barbieri, Maria Vittoria (Date of defense: 2021-01-28)

    The assessment of pesticide occurrence in different environmental compartments has become a matter of outstanding importance since its effects on exposed organisms may be considered a warning on the potential risk these ...

    Photoswitchable allosteric ligands to modulate metabotropic glutamate receptors 

    Panarello, Silvia (Date of defense: 2021-12-15)

    Photopharmacology has the main purpose to allow the control of protein activity with light. The most exploited strategy used to achieve this objective is the freely diffusible photopharmacology and it is based in the use ...

    Preparación y reactividad de compuestos organometálicos de platino de tipo [PtXR (PPh3)2] (X=HgR' o H) 

    Crespo Vicente, Margarita Ma. (Date of defense: 1986-01-01)

    Paralelamente al desarrollo de la Química Organometálica, se ha producido un notable, y en ocasiones espectacular, avance en el campo de los hidruro-complejos en el que el platino ha desempeñado un papel destacado, siendo ...

    Primary batteries paradigm redefinition within the environmental planetary boundaries 

    Navarro-Segarra, Marina (Date of defense: 2022-07-27)

    Digital technologies are generating a global transformation with economic, social, and environmental implications. Digitalization has already shown many benefits to society; however, it is also generating a fierce debate ...

    Protease inhibitors as therapeutic agents 

    Mendieta Martínez, Laura (Date of defense: 2014-06-06)

    Proteases are involved in a high number of diseases, and thus, are relevant targets. For that reason our main goal was the discovery of protease inhibitors as therapeutic agents. We focused our study in four proteases: ...