Now showing items 72-91 of 101

    Occurrence and distribution of organochlorinated pesticides and flame retardants in Spain and China 

    Zapata Corella, Pablo (Date of defense: 2022-09-19)

    In the present thesis, analytical methods based on gas chromatography coupled with mass spectrometry, both single (GC-MS) or tandem (GC-MS/MS), have been developed and optimized for the detection and quantification of ...

    Organic pollutants in indoor dust: method development, site-specific monitoring and human exposure 

    Velázquez Gómez, Miquel (Date of defense: 2019-10-21)

    Dust has been used as a surrogate of indoor organic contamination for several decades. Their concerns for human health include from sensitization effects such as allergies to toxic effects derived from those organic ...

    Origin and release of cyanotoxins in surface water reservoirs 

    Filatova, Daria (Date of defense: 2021-07-20)

    Cyanobacteria are prokaryotes and components of regular periphyton formation. Overall, there are around 2000 cyanobacterial species that live in various environments. Some cyanobacterial species are known to form blooms, ...

    Passive air and water sampling in high-altitude lakes: occurrence and distribution of legacy and emerging organic pollutants 

    Martínez Prats, Raimon (Date of defense: 2022-11-17)

    [eng] Remote high mountains allow the study of the environmental fate of legacy and emerging anthropogenic chemicals that form a worldwide diffuse background layer of pollution. Semi- volatile compounds like polychlorinated ...

    Pesticides in the environment: analysis, occurrence, impact and recommendations for their attenuation 

    Barbieri, Maria Vittoria (Date of defense: 2021-01-28)

    The assessment of pesticide occurrence in different environmental compartments has become a matter of outstanding importance since its effects on exposed organisms may be considered a warning on the potential risk these ...

    Photoswitchable allosteric ligands to modulate metabotropic glutamate receptors 

    Panarello, Silvia (Date of defense: 2021-12-15)

    Photopharmacology has the main purpose to allow the control of protein activity with light. The most exploited strategy used to achieve this objective is the freely diffusible photopharmacology and it is based in the use ...

    Preparación y reactividad de compuestos organometálicos de platino de tipo [PtXR (PPh3)2] (X=HgR' o H) 

    Crespo Vicente, Margarita Ma. (Date of defense: 1986-01-01)

    Paralelamente al desarrollo de la Química Organometálica, se ha producido un notable, y en ocasiones espectacular, avance en el campo de los hidruro-complejos en el que el platino ha desempeñado un papel destacado, siendo ...

    Primary batteries paradigm redefinition within the environmental planetary boundaries 

    Navarro-Segarra, Marina (Date of defense: 2022-07-27)

    Digital technologies are generating a global transformation with economic, social, and environmental implications. Digitalization has already shown many benefits to society; however, it is also generating a fierce debate ...

    Protease inhibitors as therapeutic agents 

    Mendieta Martínez, Laura (Date of defense: 2014-06-06)

    Proteases are involved in a high number of diseases, and thus, are relevant targets. For that reason our main goal was the discovery of protease inhibitors as therapeutic agents. We focused our study in four proteases: ...

    Protein Flexibility: From local to global motions. A computational study 

    Sánchez Martínez, Melchor (Date of defense: 2014-12-09)

    Proteins are flexible entities, and thus move. Its function is closely related to the flexibility. To carry out any function is necessary a conformational change. As protein motions imply an exchange of conformations, ...

    Simulación de una columna de paredes mojadas como reactor de sulfonación 

    Gutiérrez González, José María, 1953- (Date of defense: 1984-11-22)

    Este trabajo se ha concebido como continuación de otros anteriores, realizados en el Departamento de Química Técnica de la Facultad de Química de la Universidad de Barcelona, sobre sulfonación con SO(3) vapor en reactor ...

    Síntesis del fragmento 1-4 de la toxina II del escorpión "Androctonus australis hector". Estudio de la n-benzhidril-(4-brometil-3-nitro) benzoilamida como modelo monimérico del α-(4-bromometil-3-nitrobenzamido)benzilpoliestireno 

    Nicolás Galindo, Ernesto (Date of defense: 1988-01-01)

    Como se puede comprobar por la cantidad de ejemplos que se han descrito y siguen describiéndose en la literatura, la síntesis en fase sólida se ha erigido como un método extremadamente eficaz para la obtención de péptidos ...

    Síntesis y estudio de clusters de elementos metálicos con una nuclearidad máxima de cuatro 

    Ferrer García, Montserrat (Date of defense: 1989-01-01)

    En el Departamento de Química Inorgánica de la Universidad de Barcelona se está desarrollando desde 1984 una línea de investigación que tiene como objeto la síntesis de compuestos con enlace metal-metal en la que uno de ...

    Small molecules for modulating biological targets 

    Miret Casals, Laia (Date of defense: 2014-05-23)

    CHAPTER 1: Respiratory Infectious Diseases (RID) are diseases affecting the air passages, the bronchi and the lungs. They range from acute infections, such as pneumonia and bronchitis, to chronic conditions such as ...

    Sorption of perfluoroalkyl substances and Fluoroquinolone antibiotics in matrices of environmental interest 

    Fabregat Palau, Joel (Date of defense: 2022-09-22)

    Perfluoroalkyl substances (PFASs) and fluoroquinolone antibiotics (FQs) are pollutants of environmental interest due to their widespread presence in environmental compartments and their high toxicity and disrupting effects ...

    Structural characterization of amyloid beta oligomers with functional links associated to Alzheimer's disease 

    Puig Gomà-Camps, Eduard (Date of defense: 2019-06-20)

    Alzheimer’s disease (AD) is the most common form of dementia. It was first described in 1906 by Alois Alzheimer. Later on, in 1984 George Glenner and Colin Masters isolated the amyloid-beta (Aβ) peptide from a human brain ...

    Studies toward the synthesis of marine natural products Phormidolides B-D 

    Gil Escolano, Alejandro (Date of defense: 2018-02-16)

    Marine natural products (MNPs) are, undoubtedly, highly valuable starting points for drug-development programs. Generally, MNPs show a well-defined spatial orientation that have evolved for thousands of years to interact ...

    Study of the aggregation process of the amyloid beta-protein associated to Alzheimer's disease. Examination of pharmaceutically important small molecules. 

    Serra Vidal, Bernat (Date of defense: 2014-05-27)

    Alzheimer’s disease (AD) is a neurodegenerative disorder which major risk factor is age. Current drugs only offer symptomatic alleviation in AD, thus a disease-modifying treatment is urgent. The amyloid-β (Aβ) protein ...

    Study of transition metal carbide catalysts of group 5 in the RWGS reaction 

    Pajares Rojas, Arturo Javier (Date of defense: 2021-07-16)

    Nowadays there is a growing interest in the capture and utilization of CO2 because of the increase of its concentration in the atmosphere. Captured CO2 can be recycled through different processes to obtain several value-added ...

    Suspect screening of natural toxins in surface water reservoirs 

    Picardo, Massimo (Date of defense: 2021-02-04)

    Natural toxins include a multitude of toxic secondary metabolites produced by animals, bacteria, fungi algae, and plants that are generally not intended as environmental contaminants of concern for water quality. However, ...