Browsing Facultat de Química by Subject "615"

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Deciphering the role of peripheral and central nervous system metabotropic glutamate receptors in neuropathic pain with photoactivable ligands

Font Ingles, Joan (Date of defense: 2017-06-09)

Pain is one of the main medical problems that in several cases results into a chronic disease with limited effective treatment, thus the discovery of new drugs to fight against constitutes a big challenge nowadays. Metabotropic ...

Development and applications of photoswitchable small molecules and peptides to control protein-protein interactions and GPCR activity

Prischich, Davia (Date of defense: 2021-02-23)

Photopharmacology is an emerging field that relies on the development of photosensitive compounds to enable precise spatiotemporal control over endogenous proteins. Photochromic ligands· are designed to respond ...