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Structural studies of Heteromeric Amino acid Transporters (HATs): Validation of the first 3D structural model of a HAT (human 4F2hc/LAT2) and identification of new HAT targets for 3D‐crystallization

Álvarez Marimón, Mª Elena (Date of defense: 2014-10-27)

Heteromeric amino acid transporters (HATs) mediate the transport of amino acids through the plasma membrane. They are composed of two subunits (a heavy and a light one) linked by a conserved disulfide ...

Functional studies of 4F2hc-CD147 interaction = Estudios funcionales de la interacción 4F2hc‐CD147

Delgado Martin, Gonzalo (Date of defense: 2014-07-14)

We identified proteins that interacted with the ectodomain of 4F2hc, a plasma membrane protein with dual function as heavy subunit of the amino acid transporters and positive regulator of β1 and β3 ...

4F2hc/LAT1 heterodimer: a promising candidate for solving the first atomic structure of a heteromeric amino acid transporter = Heterodímero 4F2hc/LAT1: un candidato prometedor para resolver la primera estructura atómica de un transportador heteromérico de aminoácidos

Obando Martínez, Ana Zuleima (Date of defense: 2016-05-19)

Heteromeric amino acid transporters (HATs) are the unique solute transporters known to be composed of two subunits linked by a disulphide bridge. The heavy subunit (4F2hc or rBAT), a type II membrane ...

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Structural studies of Heteromeric Amino acid Transporters (HATs): Validation of the first 3D structural model of a HAT (human 4F2hc/LAT2) and identification of new HAT targets for 3D‐crystallization

Functional studies of 4F2hc-CD147 interaction = Estudios funcionales de la interacción 4F2hc‐CD147

4F2hc/LAT1 heterodimer: a promising candidate for solving the first atomic structure of a heteromeric amino acid transporter = Heterodímero 4F2hc/LAT1: un candidato prometedor para resolver la primera estructura atómica de un transportador heteromérico de aminoácidos

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Structural studies of Heteromeric Amino acid Transporters (HATs): Validation of the first 3D structural model of a HAT (human 4F2hc/LAT2) and identification of new HAT targets for 3D‐crystallization

Functional studies of 4F2hc-CD147 interaction = Estudios funcionales de la interacción 4F2hc‐CD147

4F2hc/LAT1 heterodimer: a promising candidate for solving the first atomic structure of a heteromeric amino acid transporter = Heterodímero 4F2hc/LAT1: un candidato prometedor para resolver la primera estructura atómica de un transportador heteromérico de aminoácidos