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Discovery of new selective antagonists of G-protein coupled receptors of therapeutic interest

Lupala, Cecylia Severin (Date of defense: 2016-01-28)

GPCR are integral membrane receptor proteins that are characterized by heptahelical transmembrane domains connected by intracellular and extracellular loops. GPCRs are an attractive class of proteins ...

Structure-function studies of bombesin and bradykinin receptors and their ligands for new therapeutic opportunities

Rasaeifar, Bahareh (Date of defense: 2020-12-10)

G-protein coupled receptors represents the largest family of membrane protein in eukaryotes cells with more than 800 members. The reason of their importance lies in their function, being responsible for ...

Structure-activity investigation on laccases by computational and site directed mutagenesis studies

Delavari, Azar (Date of defense: 2016-12-01)

Laccases belong to multi copper oxidase enzyme family (EC 1.10.3.2). Their capacity to oxidíze a wide range of substrates makes them very attractive for the industry and are growing in importance for ...

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Discovery of new selective antagonists of G-protein coupled receptors of therapeutic interest

Structure-function studies of bombesin and bradykinin receptors and their ligands for new therapeutic opportunities

Structure-activity investigation on laccases by computational and site directed mutagenesis studies

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Discovery of new selective antagonists of G-protein coupled receptors of therapeutic interest

Structure-function studies of bombesin and bradykinin receptors and their ligands for new therapeutic opportunities

Structure-activity investigation on laccases by computational and site directed mutagenesis studies