Análisis de contenidos y resultados diagnósticos en la evaluación del trastorno depresivo mayor 

    Vilar Garcés, Ana (Date of defense: 2023-03-10)

    Introducción: El Trastorno Depresivo Mayor (TDM) es una enfermedad común que limita severamente el funcionamiento psicosocial y disminuye la calidad de vida. Clínicamente, el diagnóstico pasa por la entrevista clínica ...

    Assessment of depression in the adult general population using self-reported measures : Psychometric approaches for screening and severity appraisal 

    Vilagut Saiz, Gemma (Date of defense: 2017-01-20)

    This thesis provides evidence on the validity and diagnostic accuracy of generic and specific self-reported measures, developed from different psychometric approaches, to assess depression in the general population. ...

    Cannabis en los jóvenes: patología psiquiátrica y escalas de consumo 

    Cuenca Royo, Aida Ma (Date of defense: 2014-01-22)

    El cannabis es la droga ilegal de uso más extendido en España siendo la prevalencia de su consumo elevada (17% en el último año-población de 15 a 34 años). Dado que diversos estudios muestran que sólo una pequeña proporción ...

    Characterization of autism spectrum disorder caused by alterations in complex genomic regions : molecular and pathophysiological mechanisms 

    Costa Roger, Mar (Date of defense: 2021-05-14)

    Autism Spectrum Disorder (ASD) is a group of neurodevelopmental disorders, the etiology of which is unknown in the majority of cases. Little is known about complex genomic regions containing part of the missing heritability. ...

    Common mental disorders : evaluating their impact on disability and the role of socieoeconomic factors 

    Barbaglia, María Gabriela (Date of defense: 2014-11-24)

    The general aim of this Doctoral Thesis was to assess the association of common mental disorders with disability and socioeconomic factors. These factors were considered both as important consequences (or burdens) and also ...

    Common neuroplasticity mechanisms underlying drugs and food reward 

    Guegan, Thomas (Date of defense: 2013-11-05)

    Drug addiction and some eating disorders present striking similarities in their behavioural symptoms. It has been postulated that excessive consumption of drugs of abuse and palatable food could lead to the development of ...

    Early life factors influencing neurodevelopment and the study of the interrelations between different behavioural areas 

    Júlvez Calvo, Jordi (Date of defense: 2007-09-27)

    Antecedents: No hi ha gaire coneixement sobre el neurodesenvolupament de preescolars i la seva susceptibilitat enfront a factors ambientals. <br/>Objectius: Avaluar les respostes del neurodesenvolupament en nens i les ...

    Effects of maternal separation with early weaning on cocaine addictive behaviour and consequences on neuroplasticity 

    Castro Zavala, Adriana (Date of defense: 2020-11-06)

    Early-life stress is associated with maladaptive long-lasting brain effects. Such alterations increase the likelihood of developing several psychiatric disorders. However, the molecular consequences of early-life stress ...

    Epidemiología del episodio depresivo mayor en España. Estudio descriptivo y análisis de resultados en el contexto europeo. Proyecto Esemed-España. 

    Gabilondo Cuéllar, Andrea (Date of defense: 2011-11-28)

    Objetivos del estudio: Describir la epidemiología del Episodio Depresivo Mayor (EDM) en la población general española y comparar los resultados con los datos reflejados en la literatura internacional. Métodos: Estudio ...

    Epigenetic alterations in autism spectrum disorders (ASD) 

    Homs Raubert, Aïda (Date of defense: 2015-09-15)

    The aetiology of autism spectrum disorders (ASD), a group of neurodevelopmental conditions with early onset, characterized by social and communication impairment and restricted interests, is unknown in about a third of the ...

    Explorant els determinants socials en el consum de substàncies en joves i adults a Espanya : un enfocament al consum d'alcohol 

    Teixidó i Compañó, Ester (Date of defense: 2021-03-05)

    El consum de substàncies psicoactives té importants conseqüències sanitàries, socials, econòmiques i laborals. Tot i així, el seu consum i les seves conseqüències no es distribueixen homogèniament en tota la població, ...

    Functional connectivity anomalies in the neural networks mediating motivated behavior : assessong obsessive-compulsive disorder , chronic cannabis use, Prader-Willi syndrome and Down syndrome 

    Blanco Hinojo, Laura (Date of defense: 2015-12-09)

    Compulsive, impulsive, and addictive disorders display some behavioral commonalities associated with a dysfunction in the regulation of motivated, goal-directed behavior. Relevant to motivated behavior, there is a set of ...

    Genetic associations on major depression: curation and functional analysis 

    Pérez Granado, Judith (Date of defense: 2023-03-08)

    Major depression (MD) is the leading cause of impairment worldwide. The lack of understanding of its biological underpinnings hampers the development of better diagnostic tools and treatments. Thanks to the advances in ...

    Genetic diversity of " brain genes" across worldwide 

    Gardner, Michelle (Date of defense: 2007-06-25)

    El treball presentat en aquesta tesi és un estudi de la diversitat genètica en un conjunt de gens implicats en funcions neurològiques ("Gens cerebrals"). Hom ha examinat vint-i-dos gens implicats en els sistemes de ...

    Genetic variation and complex rearrangements in Autism Spectrum Disorders: implications for genetic counseling 

    Codina i Solà, Marta (Date of defense: 2016-07-14)

    The etiology of Autism Spectrum Disorders (ASD) remains unknown for most of the cases, in spite of its strong genetic component. A greater knowledge of its genetic basis would result in many benefits, including specific ...

    Involvement of the endogenous opioid and cannabinoid systems in addictive like-behaviours 

    Mancino, Samantha (Date of defense: 2016-01-22)

    The increase incidence of obesity and eating disorders represents a major health problem in developed countries. The low rate of success of treatments to prevent or reverse obesity, and overeating that causes it, highlights ...

    Mecanismes moleculars en el transtorn de la conducta alimentària: estudis en humans i en model murins 

    Mercader Bigas, Josep Maria (Date of defense: 2008-07-11)

    Els trastorns de la conducta alimentària (TCA) tenen una etiologia complexa en la que hi intervenen factors de predisposició socioculturals, ambientals i genètics. S'ha aprofundit en les bases moleculars dels TCA mitjançant ...

    Molecular mechanisms underlying the effects of cannabinoids in the brain 

    Puighermanal Puigvert, Emma (Date of defense: 2011-09-27)

    The endocannabinoid system is an endogenous neuromodulatory system that regulates a plethora of physiological functions, including the control of movement, memory, anxiety, and pain, among others. Cannabinoid compounds are ...

    Neural networks connecting emotion and cognition assessed in psychopaths, cocaine users and obsessive-compulsive disorder using MRI 

    Contreras Rodríguez, Oren (Date of defense: 2013-09-12)

    Emotional processing is fundamental for normal socialization, interpersonal interactions, successful decision-making and overall to self-regulate behavior according to each context. Adequate emotional processing relies ...

    Neural substrates of psychotic-like states and cognitive impairment in a mouse model of schizophrenia and subsequent rescue by antipsychotic drugs 

    Delgado Sallent, Cristina (Date of defense: 2021-12-17)

    Disruption of communication in brain circuits involving the prefrontal cortex (PFC) and the hippocampus (HPC) has been suggested to be a hallmark characteristic of schizophrenia. Therefore, a better understanding of the ...