Solé Morata, Neus (Date of defense: 2017-12-15)
The Y chromosome is the longest non-recombining DNA sequence of the human genome. This avoidance of recombination, together with its paternal inheritance, makes the Y chromosome a powerful tool with ...
Toll i Riera, Macarena (Date of defense: 2012-03-28)
Actualment, degut a la disponibilitat d’un gran nombre de genomes seqüenciats, el camp de la genòmica comparativa està experimentant grans avenços. Ara són possibles una àmplia gama d’estudis que fins ...
Santesmasses Ruiz, Didac (Date of defense: 2016-12-12)
La selenocïsteina és coneguda com a l'aminoàcid 21. Les selenoproteïnes incorporen selenocïsteina en resposta a codons UGA específics mitjançant un mecanisme de recodificació, el qual és present en els ...
Ruiz Orera, Jorge (Date of defense: 2017-01-19)
Aquesta tesi investiga els mecanismes de formació i evolució de gens de novo utilitzant seqüenciació massiva de transcrits complerts i de fragments protegits per ribosomes. Hem identificat milers de ...
Arcas Mantas, Aida (Date of defense: 2013-04-25)
The DNA Damage response is a crucial signaling network that preserves genome integrity. This network is an ensemble of distinct but often overlapping sub-networks, where participating components exert ...
López Escardó, David (Date of defense: 2018-01-15)
Opisthokonta is an eukaryotic supergroup that contains Metazoa, Fungi and their unicellular relatives. Therefore, this group provides an ideal framework to study distinct unicellular-multicellular ...
Han, Sojung (Date of defense: 2019-10-16)
Bonobos are an interesting species to study due to their unique evolutionary features such as a peaceful social nature and hypersexual behavior. The prolonged exaggerated sexual swelling in females ...
Farré Ramon, Xavier (Date of defense: 2022-07-01)
Ageing is a very complex phenotype that has been widely studied, but is still largely unknown. Most of the studies focus on a single species, or on performing genome wide association studies in human ...
Sodaei, Reza (Date of defense: 2020-05-22)
How do genomes generate different tissues, behaviours, individuals or species? We try to identify parts of the human transcriptome that we found only in a tissue. Then, we focus on inter-individual ...
García Pérez, Raquel (Date of defense: 2019-01-29)
The evolution of the human phenotype involved gene regulatory innovations. Comparative functional epigenomic studies are a powerful tool with potential to shed light on many long-standing questions ...