Planas Iglesias, Joan (Date of defense: 2013-01-21)
Proteins are indispensable players in virtually all biological events. The functions of proteins are determined by their three dimensional (3D) structure and coordinated through intricate networks of ...
Aguirre Plans, Joaquim (Date of defense: 2021-07-14)
El funcionament intern de les cèl·lules pot entendre’s com un conjunt d’interaccions entre biomolècules, formant una xarxa que coneixem amb el nom d’interactoma. Els fàrmacs i malalties poden considerar-se ...
Marín López, Manuel Alejandro (Date of defense: 2017-01-13)
Proteins are involved in almost all cell processes, with physical interaction between them being key to their function and dictated by its 3D structure. Hence, the study of protein-protein interactions ...
Meseguer Donlo, Alberto (Date of defense: 2021-07-02)
Las células de nuestro cuerpo son capaces de tener comportamientos y morfologías completamente diferentes, pese a contener el mismo material genético. Entre los mecanismos que permiten esta diversidad ...
Fornés Crespo, Oriol (Date of defense: 2015-01-21)
Protein-DNA interactions are indispensable players in the daily activities of cells. DNA-binding proteins regulate gene expression and are responsible of DNA replication, packaging, repair and recombination. ...
Stein, Amelie (Date of defense: 2010-06-11)
Proteins and protein interactions are involved in virtually all processes of life. Here we study interactions between globular domains and short linear motifs, which form a small interface ideal for ...
Jorba Argemí, Guillem (Date of defense: 2023-04-13)
El procés de descobriment i desenvolupament de fàrmacs (DDD) és costós tant econòmic com temporalment, i el qual resulta en nivells d'èxit molt reduïts. Una gran quantitat de compostos son analitzats i ...
Güney, Emre (Date of defense: 2012-09-25)
The cell is governed by the complex interactions among various types of biomolecules. Coupled with environmental factors, variations in DNA can cause alterations in normal gene function and lead to a ...
Bonet Martínez, Jaume (Date of defense: 2015-01-30)
Proteins are the basic functional and structural blocks of life. Knowledge of their structure and function is key to understand how it works. Lately, the gap between new discovered proteins and ...
García-García, Javier (Date of defense: 2015-01-23)
The use of protein-protein interaction networks has become crucial due to the emergence of systems biology. The completeness and quality of networks, crucial to understand the biochemical mechanisms ...