Mostrando ítems 1-10 de 11
Vandelli, Andrea (Fecha de defensa: 2023-04-19)
Ribonucleoprotein condensates such as stress granules (SGs) and processing bodies (PBs) form in response to specific stimuli in the cell. Even though the key protein and RNA elements of these condensates ...
Dasti, Alessandro (Fecha de defensa: 2020-01-22)
The molecular basis that sustain embryonic stem cell (ESCs) pluripotency and their differentiation in all the types of somatic cells is subject of intensive research. Recently, the potential involvement ...
Antonelli, Maria Carla (Fecha de defensa: 2021-03-24)
During the last decades the non-coding portion of the genome became subject of intense research due to its contribution to the complexity of biological and pathological processes. CircRNAs are a class ...
Delli Ponti, Riccardo (Fecha de defensa: 2019-01-16)
The secondary structure of an RNA molecule is fundamental for its function. However, structural conservation and the structure of RNA in vivo are still poorly understood. Data from recent high-throughput ...
Cid Samper, Fernando (Fecha de defensa: 2020-01-27)
Ribonucleoprotein granules (RNP granules) are liquid-liquid phase separated complexes composed mainly by proteins and RNA. They are responsible of many processes involved in RNA regulation. Alterations ...
Agostini, Federico (Fecha de defensa: 2014-06-16)
RNA-binding proteins (RBPs) control the fate of a multitude of coding and non-coding transcripts. Formation of ribonucleoprotein (RNP) complexes fine-tunes regulation of post-transcriptional events and ...
Klus, Petr (Fecha de defensa: 2016-07-12)
The purpose of my doctoral studies was to develop an algorithm for large-scale analysis of protein sets. This thesis outlines the methodology and technical work performed as well as relevant biological ...
Armaos, Alexandros (Fecha de defensa: 2020-01-23)
Despite what was previously considered, the role of RNA is not only to carry the genetic information from DNA to proteins. Indeed, RNA has proven to be implicated in more complex cellular processes. ...
Cirillo, Davide (Fecha de defensa: 2016-05-09)
The purpose of my doctoral studies has been the development of bioinformatics methods to quantitatively evaluate associations between proteins and nucleic acids (NAs). This thesis aims at providing ...
Marchese, Domenica (Fecha de defensa: 2016-11-14)
The role of RNA processing in the pathogenesis of neurodegenerative diseases is still poorly understood. α-synuclein (SNCA) is a presynaptic neuronal protein known as the major component of Lewy bodies, ...