The role of the Smc5/6 complex and the Mms21 SUMO Ligase in the maintenance of genomic integrity 

Bermúdez López, Marcelino (Date of defense: 2014-09-22)

The Structural Maintenance of Chromosomes (SMC) Smc5/6 complex has a poorly understood function in chromosome repair and segregation. In this study, we show that the dissolution of DNA-mediated connections requires the ...