Universitat de Barcelona
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Genomic imprinting is an epigenetic phenomenon resulting in the monoallelic expression of a subset of genes in a parent-of-origin-specific manner. In general, the promoters of these transcripts contain differentially ...
Els telòmers són estructures dels extrems dels cromosomes linials d’organismes eucariotes. La longitud telomèrica es manté mitjançant l’enzim telomerasa en la majoria d’eucariotes, on s’hi troba altament conservat. Drosophila, ...
B-cell non-Hodgkin lymphoma (B-NHL) of pediatric and young adult population is a diverse group of neoplasms predominantly composed of aggressive B-cell lymphomas from the germinal center (GC). Molecular characterization ...
Diabetes mellitus is a heterogeneous group of metabolic diseases characterized by impaired blood glucose homeostasis that affects more than 415 million people worldwide and is a leading cause of mortality. The most prevalent ...
[eng] Diabetes mellitus is a heterogeneous group of metabolic diseases characterized by impaired blood glucose homeostasis that affects more than 415 million people worldwide and is a leading cause of mortality. The most ...
The proper function of the immune system requires complex regulatory mechanisms and a highly strict balance in the amount and function of immune and non-immune elements. Part of the primary immunodeficiencies result from ...
[eng] Monocytes are highly plastic cells and possess the ability to differentiate into cell types with very different immunological properties. Depending on the external stimuli and the specific immune context, they can ...
Cancer was reported as the second leading cause of death in 2018 by the World Health Organisation. Cancer is defined as the set of diseases that proceeds in multiple phases generating a transformation lead by an accumulation ...
Colorectal cancer (CRC) is one of the malignant neoplasms with higher incidence and mortality in Spain, Europe and worldwide. As a complex disease, both environmental and genetic factors influence CRC predisposition. Up ...
La via de Calcineurina (Cn)- Factor Nuclear de Cèl·lules T Activades (NFAT) ha estat descrita clàssicament com a via de senyalització essencial en el funcionament de les cèl·lules T del sistema immunològic i amb els NFATc ...
STUDY I HYPOTHESIS Genetic alterations have already been recognized as major etiological factors for ASD and ID, of which RTT is an example. In addition to the contribution of polymorphic variants that confer low or ...
La sirtuïna 1 (SirT1), una desacetilasa depenent de NAD, promou la formació de l’heterocromatina facultativa (HF) desacetilant H4K16Ac, H3K9Ac i H1K26Ac i establint marcadors d’heterocromatina via interacció amb la histona ...
